5-MeO-MPT

5-MeO-MPT

Clinical data
Other names	5-Methoxy-N-methyl-N-propyltryptamine
ATC code	None
Identifiers
IUPAC name N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-methylpropan-1-amine
PubChem CID	74405225
Chemical and physical data
Formula	C15H22N2O
Molar mass	246.354 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCN(C)CCC1=CNC2=C1C=C(C=C2)OC
InChI InChI=1S/C15H22N2O/c1-4-8-17(2)9-7-12-11-16-15-6-5-13(18-3)10-14(12)15/h5-6,10-11,16H,4,7-9H2,1-3H3 Key:YQHARYRPMKOJND-UHFFFAOYSA-N

5-MeO-MPT, also known as 5-methoxy-N-methyl-N-propyltryptamine, is a chemical compound of the tryptamine and 5-methoxytryptamine families. ^{[1] [2] [3] [4] [5] [6]} It is closely related to the known psychedelic tryptamine and designer drug 4-HO-MPT as well as to methylpropyltryptamine (MPT). ^{[7] [8] [9]}

See also

• Substituted tryptamine
• Methylpropyltryptamine (MPT)
• 4-HO-MPT

References

1. Brandt SD, Freeman S, Fleet IA, Alder JF (September 2005). "Analytical chemistry of synthetic routes to psychoactive tryptamines. Part III. Characterisation of the Speeter and Anthony route to N,N-dialkylated tryptamines using CI-IT-MS-MS". The Analyst. 130 (9): 1258–1262. Bibcode:2005Ana...130.1258B. doi:10.1039/b504001a. PMID   16096671.
2. Brandt SD, Freeman S, Fleet IA, McGagh P, Alder JF (March 2005). "Analytical chemistry of synthetic routes to psychoactive tryptamines. Part II. Characterisation of the Speeter and Anthony synthetic route to N,N-dialkylated tryptamines using GC-EI-ITMS, ESI-TQ-MS-MS and NMR". The Analyst. 130 (3): 330–344. Bibcode:2005Ana...130..330B. doi:10.1039/b413014f. PMID   15724162.
3. Brandt SD, Tirunarayanapuram SS, Freeman S, Dempster N, Barker SA, Daley PF, et al. (2008). "Microwave-accelerated synthesis of psychoactive deuterated N,N-dialkylated-[α,α,β,β-d4]-tryptamines". Journal of Labelled Compounds and Radiopharmaceuticals. 51 (14): 423–429. doi:10.1002/jlcr.1557. ISSN   0362-4803 . Retrieved 10 October 2025.
4. Brandt SD, Martins CP (2010). "Analytical methods for psychoactive N,N-dialkylated tryptamines". TrAC Trends in Analytical Chemistry. 29 (8): 858–869. doi:10.1016/j.trac.2010.04.008 . Retrieved 10 October 2025.
5. Martins CP, Freeman S, Alder JF, Passie T, Brandt SD (2010). "Profiling psychoactive tryptamine-drug synthesis by focusing on detection using mass spectrometry". TrAC Trends in Analytical Chemistry. 29 (4): 285–296. doi:10.1016/j.trac.2010.01.009 . Retrieved 10 October 2025.
6. Warren, A. (2024). Structural Evaluation of Mechanisms Underlying Serotonin Receptor Function (Doctoral dissertation, Icahn School of Medicine at Mount Sinai). https://www.proquest.com/openview/327b474bc8be3e1cabcd28a34c3b4f38/
7. Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN   0-9630096-9-9. OCLC   38503252. https://www.erowid.org/library/books_online/tihkal/tihkal23.shtml
8. Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD (May 2020). "Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species". Neuropharmacology. 167 107933. doi:10.1016/j.neuropharm.2019.107933. PMC   9191653 . PMID   31917152. Table 4 Human potency data for selected hallucinogens. [...]
9. Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2021). "Identification of six tryptamine derivatives as designer drugs in illegal products". Forensic Toxicology. 39 (1): 248–258. doi:10.1007/s11419-020-00556-5. ISSN   1860-8965 . Retrieved 9 October 2025.

External links

• 5-MeO-MPT - Isomer Design