ADB-5'F-BUTINACA

Last updated
ADB-5'F-BUTINACA
ADB-5'F-BUTINACA structure.png
Identifiers
  • N-(1-amino-3,3-dimethyl-1-oxo-2-butanyl)-1-butyl-1H-5-fluoroindazole-3-carboxamide
PubChem CID
ChemSpider
Chemical and physical data
Formula C18H25FN4O2
Molar mass 348.422 g·mol−1
3D model (JSmol)
  • O=C(N[C@H](C(N)=O)C(C)(C)C)C1=NN(CCCC)C2=C1C=C(F)C=C2
  • InChI=1S/C18H25FN4O2/c1-5-6-9-23-13-8-7-11(19)10-12(13)14(22-23)17(25)21-15(16(20)24)18(2,3)4/h7-8,10,15H,5-6,9H2,1-4H3,(H2,20,24)(H,21,25)/t15-/m1/s1
  • Key:JORGRORAECYNOJ-OAHLLOKOSA-N

ADB-5'F-BUTINACA is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist. It was synthesised as part of investigations into related compounds such as ADB-5'Br-BUTINACA and MDMB-5'Br-BUTINACA, and confirmed that fluorination of the indazole 5-position increases potency in a similar manner to bromination. [1]

See also

References

  1. Deventer MH, Persson M, Norman C, Liu H, Connolly MJ, Daéid NN, McKenzie C, Gréen H, Stove CP (October 2023). "In vitro cannabinoid activity profiling of generic ban-evading brominated synthetic cannabinoid receptor agonists and their analogs". Drug Testing and Analysis. 16 (6): 616–628. doi:10.1002/dta.3592. PMID   37903509. S2CID   264671035.