This is a list of television programs once broadcast by the American television network CBS that have ended their runs on the network.
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| Studio One | November 7, 1948 | September 29, 1958 | 10 | |
| City Hospital | March 25, 1952 | October 1, 1953 | 1 | |
| The Public Defender | March 11, 1954 | June 23, 1955 | 1 | |
| The Telltale Clue | July 8, 1954 | September 23, 1954 | 1 | |
| Lassie | September 12, 1954 | March 8, 1971 | Seasons 1–17 only Moved to first-run syndication for Seasons 18–19 | 17 |
| Climax! | October 7, 1954 | June 26, 1958 | 4 | |
| Gunsmoke | September 7, 1955 | March 31, 1975 | 20 | |
| Alfred Hitchcock Presents | October 2, 1955 | July 3, 1964 | Seasons 1–5, 8–9 only Moved to NBC for seasons 6–7, 10 | 7 |
| The 20th Century Fox Hour | October 5, 1955 | June 12, 1957 | 2 | |
| Have Gun – Will Travel | September 14, 1957 | April 20, 1963 | 6 | |
| Perry Mason | September 21, 1957 | May 22, 1966 | 9 | |
| Armstrong Circle Theatre | November 27, 1957 | June 5, 1963 | Seasons 8–14 only Seasons 1–7 aired on NBC | 7 |
| Wanted Dead or Alive | September 6, 1958 | March 29, 1961 | 3 | |
| Yancy Derringer | October 2, 1958 | June 4, 1959 | 1 | |
| Rawhide | January 9, 1959 | December 7, 1965 | 8 | |
| Hotel de Paree | October 2, 1959 | June 3, 1960 | 1 | |
| The Twilight Zone (1959) | October 2, 1959 | June 19, 1964 | 5 | |
| Diagnosis: Unknown | July 5, 1960 | September 20, 1960 | 1 | |
| Route 66 | October 7, 1960 | March 20, 1964 | 4 | |
| The Defenders (1961) | September 16, 1961 | May 13, 1965 | 4 | |
| Window on Main Street | October 2, 1961 | May 23, 1962 | 1 | |
| The Investigators | October 5, 1961 | December 28, 1961 | 1 | |
| The Lloyd Bridges Show | September 11, 1962 | May 28, 1963 | 1 | |
| The Alfred Hitchcock Hour | September 20, 1962 | July 3, 1964 | Seasons 1–2 only Moved to NBC for season 3 | 2 |
| The Nurses | September 27, 1962 | May 11, 1965 | Renamed The Doctors and the Nurses on September 26, 1963 | 3 |
| Vacation Playhouse | July 22, 1963 | August 28, 1967 | 5 | |
| For the People | January 31, 1965 | May 9, 1965 | 1 | |
| Our Private World | May 5, 1965 | September 10, 1965 | 1 | |
| Lost in Space | September 15, 1965 | March 6, 1968 | 3 | |
| The Wild Wild West | September 17, 1965 | April 4, 1969 | 4 | |
| The Loner | September 18, 1965 | March 12, 1966 | 1 | |
| Daktari | January 11, 1966 | January 15, 1969 | 4 | |
| Jericho | September 15, 1966 | January 19, 1967 | 1 | |
| Mission: Impossible | September 17, 1966 | March 30, 1973 | 7 | |
| Cimarron Strip | September 7, 1967 | March 7, 1968 | 1 | |
| Gentle Ben | September 10, 1967 | August 31, 1969 | 2 | |
| Mannix | September 16, 1967 | April 13, 1975 | 8 | |
| The Prisoner | June 1, 1968 | September 21, 1968 | 1 | |
| Premiere | July 1, 1968 | September 9, 1968 | 1 | |
| Hawaii Five-O | September 20, 1968 | April 5, 1980 | 12 | |
| Lancer | September 24, 1968 | June 23, 1970 | 2 | |
| Medical Center | September 24, 1969 | September 6, 1976 | 7 | |
| Storefront Lawyers | September 16, 1970 | April 14, 1971 | Renamed Men at Law on February 3, 1971 | 1 |
| Cannon | September 14, 1971 | March 3, 1976 | 5 | |
| Bearcats! | September 16, 1971 | December 30, 1971 | 1 | |
| O'Hara, U.S. Treasury | September 17, 1971 | March 10, 1972 | 1 | |
| Cade's County | September 19, 1971 | April 9, 1972 | 1 | |
| The Waltons | September 14, 1972 | June 4, 1981 | 9 | |
| Barnaby Jones | January 28, 1973 | April 3, 1980 | 8 | |
| The New Perry Mason | September 16, 1973 | January 20, 1974 | 1 | |
| Hawkins | October 2, 1973 | September 3, 1974 | 1 | |
| Shaft | October 9, 1973 | February 19, 1974 | 1 | |
| Kojak | October 24, 1973 | March 18, 1978 | 5 | |
| Apple's Way | February 10, 1974 | January 12, 1975 | 2 | |
| Sons and Daughters (1974) | September 11, 1974 | November 6, 1974 | 1 | |
| Planet of the Apes | September 13, 1974 | December 20, 1974 | 1 | |
| Switch | September 9, 1975 | August 20, 1978 | 3 | |
| Kate McShane | September 10, 1975 | November 12, 1975 | 1 | |
| Three for the Road | September 14, 1975 | November 30, 1975 | 1 | |
| The Blue Knight | December 10, 1975 | October 20, 1976 | 2 | |
| Sara | February 13, 1976 | May 7, 1976 | 1 | |
| Delvecchio | September 9, 1976 | March 13, 1977 | 1 | |
| Spencer's Pilots | September 17, 1976 | November 19, 1976 | 1 | |
| Executive Suite | September 20, 1976 | February 11, 1977 | 1 | |
| Code R | January 21, 1977 | June 10, 1977 | 1 | |
| The Andros Targets | January 31, 1977 | May 16, 1977 | 1 | |
| Hunter | February 18, 1977 | May 27, 1977 | 1 | |
| Nashville 99 | April 1, 1977 | April 22, 1977 | 1 | |
| The Fitzpatricks | September 5, 1977 | January 10, 1978 | 1 | |
| Rafferty | September 5, 1977 | November 28, 1977 | 1 | |
| Logan's Run | September 16, 1977 | February 6, 1978 | 1 | |
| The New Adventures of Wonder Woman | September 16, 1977 | September 11, 1979 | Seasons 2–3 only Season 1 aired on ABC | 2 |
| The Amazing Spider-Man | September 19, 1977 | July 6, 1979 | 2 | |
| Lou Grant | September 20, 1977 | September 13, 1982 | 5 | |
| The Incredible Hulk | March 10, 1978 | May 12, 1982 | 5 | |
| Dallas | April 2, 1978 | May 3, 1991 | 14 | |
| The Paper Chase | September 9, 1978 | April 24, 1979 | Season 1 only Moved to Showtime for seasons 2–4 | 1 |
| Kaz | September 10, 1978 | April 22, 1979 | 1 | |
| The American Girls | September 23, 1978 | November 11, 1978 | 1 | |
| The White Shadow | September 27, 1978 | March 16, 1981 | 3 | |
| The Dukes of Hazzard | January 26, 1979 | February 8, 1985 | 7 | |
| Trapper John, M.D. | September 23, 1979 | September 4, 1986 | 7 | |
| California Fever | September 25, 1979 | December 11, 1979 | 1 | |
| Big Shamus, Little Shamus | September 29, 1979 | October 6, 1979 | 1 | |
| Paris | September 29, 1979 | January 15, 1980 | 1 | |
| Salem's Lot | November 17, 1979 | November 24, 1979 | Miniseries | 1 |
| Young Maverick | November 28, 1979 | January 30, 1980 | 1 | |
| Knots Landing | December 27, 1979 | May 13, 1993 | 14 | |
| Scruples | February 25, 1980 | February 27, 1980 | Miniseries | 1 |
| Hagen | March 15, 1980 | April 24, 1980 | 1 | |
| Palmerstown, U.S.A. | March 20, 1980 | June 9, 1981 | Renamed Palmerstown on March 17, 1981 | 2 |
| Enos | November 12, 1980 | May 20, 1981 | 1 | |
| Secrets of Midland Heights | December 6, 1980 | January 24, 1981 | 1 | |
| Magnum, P.I. (1980) | December 11, 1980 | May 8, 1988 | 8 | |
| Riker | March 14, 1981 | April 11, 1981 | 1 | |
| Nurse | April 2, 1981 | May 21, 1982 | 2 | |
| Jessica Novak | November 5, 1981 | November 26, 1981 | 1 | |
| Shannon | November 11, 1981 | April 7, 1982 | 1 | |
| Simon & Simon | November 24, 1981 | December 31, 1988 | 8 | |
| Falcon Crest | December 4, 1981 | May 17, 1990 | 9 | |
| Q.E.D. | March 23, 1982 | April 27, 1982 | 1 | |
| Cagney & Lacey | March 25, 1982 | May 16, 1988 | 7 | |
| Seven Brides for Seven Brothers | September 19, 1982 | March 23, 1983 | 1 | |
| Bring 'Em Back Alive | September 24, 1982 | May 31, 1983 | 1 | |
| Tucker's Witch | October 6, 1982 | June 9, 1983 | 1 | |
| Wizards and Warriors | February 26, 1983 | May 14, 1983 | 1 | |
| The Mississippi | March 25, 1983 | March 6, 1984 | 1 | |
| Zorro and Son | April 6, 1983 | June 1, 1983 | 1 | |
| Emerald Point N.A.S. | September 26, 1983 | March 12, 1984 | 1 | |
| Cutter to Houston | October 1, 1983 | December 31, 1983 | 1 | |
| Scarecrow and Mrs. King | October 3, 1983 | May 28, 1987 | 4 | |
| Whiz Kids | October 5, 1983 | June 2, 1984 | 1 | |
| Airwolf | January 22, 1984 | March 29, 1986 | Seasons 1–3 only Moved to USA Network for season 4 | 3 |
| Mickey Spillane's Mike Hammer | January 28, 1984 | May 13, 1987 | Renamed The New Mike Hammer on September 22, 1986 | 3 |
| George Washington | April 8, 1984 | April 11, 1984 | Miniseries | 1 |
| Cover Up | September 22, 1984 | April 6, 1985 | 1 | |
| Murder, She Wrote | September 30, 1984 | May 19, 1996 | 12 | |
| Crazy Like a Fox | December 30, 1984 | May 3, 1986 | 2 | |
| Otherworld | January 26, 1985 | March 16, 1985 | 1 | |
| Detective in the House | March 15, 1985 | April 19, 1985 | 1 | |
| Space | April 14, 1985 | April 18, 1985 | Miniseries | 1 |
| Hometown | August 22, 1985 | October 15, 1985 | 1 | |
| The Equalizer (1985) | September 18, 1985 | August 24, 1989 | 4 | |
| T. J. Hooker | September 25, 1985 | June 28, 1986 | Season 5 only Seasons 1–4 aired on ABC | 1 |
| The Twilight Zone (1985) | September 27, 1985 | July 17, 1987 | Seasons 1–2 only Moved to first-run syndication for season 3 | 2 |
| Bridges to Cross | April 24, 1986 | June 12, 1986 | 1 | |
| The Wizard | September 9, 1986 | March 12, 1987 | 1 | |
| George Washington II: The Forging of a Nation | September 21, 1986 | September 22, 1986 | Miniseries | 1 |
| Kay O'Brien | September 25, 1986 | November 13, 1986 | 1 | |
| Downtown | September 27, 1986 | April 22, 1987 | 1 | |
| Echoes in the Darkness | November 1, 1986 | November 2, 1986 | Miniseries | 1 |
| Fresno | November 16, 1986 | November 20, 1986 | Miniseries | 1 |
| Shell Game | January 8, 1987 | February 12, 1987 | 1 | |
| I'll Take Manhattan | March 1, 1987 | March 22, 1987 | Miniseries | 1 |
| Spies | March 2, 1987 | April 14, 1987 | 1 | |
| Houston Knights | March 11, 1987 | June 10, 1988 | 2 | |
| CBS Summer Playhouse | June 12, 1987 | August 22, 1989 | 3 | |
| The Oldest Rookie | September 16, 1987 | January 13, 1988 | 1 | |
| Wiseguy | September 16, 1987 | December 8, 1990 | 4 | |
| Tour of Duty | September 24, 1987 | April 28, 1990 | 3 | |
| Beauty and the Beast | September 25, 1987 | August 4, 1990 | 3 | |
| Jake and the Fatman | September 26, 1987 | May 6, 1992 | 5 | |
| The Law & Harry McGraw | September 27, 1987 | February 10, 1988 | 1 | |
| Leg Work | October 3, 1987 | November 7, 1987 | 1 | |
| High Mountain Rangers | January 2, 1988 | April 9, 1988 | 1 | |
| Blue Skies | June 13, 1988 | August 1, 1988 | 1 | |
| Paradise | October 27, 1988 | May 10, 1991 | Renamed Guns of Paradise on January 4, 1991 | 3 |
| Dirty Dancing | October 29, 1988 | January 21, 1989 | 1 | |
| Almost Grown | November 27, 1988 | February 20, 1989 | 1 | |
| TV 101 | November 29, 1988 | March 25, 1989 | 1 | |
| Dolphin Cove | January 21, 1989 | March 11, 1989 | 1 | |
| Lonesome Dove | February 5, 1989 | February 8, 1989 | Miniseries | 1 |
| Hard Time on Planet Earth | March 1, 1989 | June 21, 1989 | 1 | |
| Rescue 911 | April 18, 1989 | August 27, 1996 | 7 | |
| Jesse Hawkes | April 22, 1989 | May 27, 1989 | 1 | |
| Wolf | September 13, 1989 | June 28, 1990 | 1 | |
| Island Son | September 16, 1989 | March 15, 1990 | 1 | |
| Peaceable Kingdom | September 20, 1989 | November 15, 1990 | 1 | |
| Top of the Hill | September 21, 1989 | November 30, 1989 | 1 | |
| Snoops | September 22, 1989 | July 6, 1990 | 1 | |
| Max Monroe: Loose Cannon | January 5, 1990 | April 19, 1990 | 1 | |
| Grand Slam | January 28, 1990 | March 14, 1990 | 1 | |
| The Bradys | February 9, 1990 | March 9, 1990 | 1 | |
| Northern Exposure | July 12, 1990 | July 26, 1995 | 6 | |
| E.A.R.T.H. Force | September 16, 1990 | September 29, 1990 | 1 | |
| The Trials of Rosie O'Neill | September 17, 1990 | May 30, 1992 | 2 | |
| The Flash | September 20, 1990 | May 18, 1991 | 1 | |
| WIOU | October 24, 1990 | March 20, 1991 | 1 | |
| Over My Dead Body | November 2, 1990 | June 20, 1991 | 1 | |
| Broken Badges | November 24, 1990 | June 20, 1991 | 1 | |
| Sons and Daughters (1991) | January 4, 1991 | March 1, 1991 | 1 | |
| The Antagonists | March 21, 1991 | May 30, 1991 | 1 | |
| Dark Justice | April 5, 1991 | September 28, 1993 | 3 | |
| Sweating Bullets | April 8, 1991 | October 18, 1993 | 3 | |
| Golden Years | July 16, 1991 | August 22, 1991 | Miniseries | 1 |
| P.S. I Luv U | September 15, 1991 | January 4, 1992 | 1 | |
| Palace Guard | October 18, 1991 | November 1, 1991 | 1 | |
| Silk Stalkings | November 7, 1991 | June 10, 1993 | Seasons 1–2 only Moved to USA Network for seasons 3–8 | 2 |
| Hearts Are Wild | January 10, 1992 | March 13, 1992 | 1 | |
| Tequila and Bonetti | January 17, 1992 | April 18, 1992 | 1 | |
| The Human Factor | April 16, 1992 | May 28, 1992 | 1 | |
| Raven | June 19, 1992 | April 30, 1993 | 2 | |
| 2000 Malibu Road | August 23, 1992 | September 9, 1992 | 1 | |
| Middle Ages | September 3, 1992 | October 1, 1992 | 1 | |
| Angel Street | September 15, 1992 | October 3, 1992 | 1 | |
| The Hat Squad | September 16, 1992 | January 23, 1993 | 1 | |
| Picket Fences | September 18, 1992 | June 26, 1996 | 4 | |
| In the Heat of the Night | October 28, 1992 | May 16, 1995 | Seasons 6–7 only Seasons 1–5 aired on NBC | 2 |
| Sinatra | November 8, 1992 | November 9, 1992 | Miniseries | 1 |
| Dr. Quinn, Medicine Woman | January 1, 1993 | May 16, 1998 | 6 | |
| Walker, Texas Ranger | April 21, 1993 | May 19, 2001 | 8 | |
| Angel Falls | August 26, 1993 | September 30, 1993 | 1 | |
| Harts of the West | September 25, 1993 | June 18, 1994 | 1 | |
| Diagnosis: Murder | September 29, 1993 | May 11, 2001 | 8 | |
| South of Sunset | October 27, 1993 | 1 | ||
| Return to Lonesome Dove | November 14, 1993 | November 17, 1993 | Miniseries | 1 |
| Second Chances | December 2, 1993 | February 19, 1994 | 1 | |
| Burke's Law | January 7, 1994 | July 28, 1995 | 2 | |
| The Road Home | March 5, 1994 | April 16, 1994 | 1 | |
| Christy | April 3, 1994 | August 2, 1995 | 2 | |
| Due South | April 26, 1994 | May 15, 1996 | Seasons 1–2 only Moved to CTV for seasons 3–4 | 2 |
| Hotel Malibu | August 4, 1994 | September 8, 1994 | 1 | |
| One West Waikiki | August 4, 1994 | May 25, 1996 | 2 | |
| Under Suspicion | September 16, 1994 | March 10, 1995 | 1 | |
| Chicago Hope | September 18, 1994 | May 4, 2000 | 6 | |
| Touched by an Angel | September 21, 1994 | April 27, 2003 | 9 | |
| Under One Roof | March 14, 1995 | April 18, 1995 | 1 | |
| Central Park West | September 13, 1995 | June 28, 1996 | 1 | |
| Courthouse | September 13, 1995 | November 15, 1995 | 1 | |
| The Client | September 17, 1995 | April 16, 1996 | 1 | |
| American Gothic | September 22, 1995 | July 11, 1996 | 1 | |
| New York News | September 28, 1995 | November 30, 1995 | 1 | |
| Streets of Laredo | November 12, 1995 | November 14, 1995 | Miniseries | 1 |
| Nash Bridges | March 29, 1996 | May 4, 2001 | 6 | |
| Undue Influence | September 15, 1996 | September 17, 1996 | Miniseries | 1 |
| Promised Land | September 17, 1996 | May 20, 1999 | 3 | |
| Moloney | September 19, 1996 | May 22, 1997 | 1 | |
| Mr. & Mrs. Smith | September 20, 1996 | November 8, 1996 | 1 | |
| Early Edition | September 28, 1996 | May 27, 2000 | 4 | |
| EZ Streets | October 27, 1996 | April 2, 1997 | 1 | |
| Titanic | November 17, 1996 | November 19, 1996 | Miniseries | 1 |
| JAG | January 3, 1997 | April 29, 2005 | Seasons 2–10 only Season 1 aired on NBC | 9 |
| Orleans | January 7, 1997 | April 10, 1997 | 1 | |
| Feds | March 5, 1997 | April 9, 1997 | 1 | |
| The Last Don | May 11, 1997 | May 14, 1997 | Miniseries | 1 |
| Brooklyn South | September 22, 1997 | April 29, 1998 | 1 | |
| Dellaventura | September 23, 1997 | January 13, 1998 | 1 | |
| The Magnificent Seven | January 3, 1998 | July 3, 2000 | 3 | |
| L.A. Doctors | September 21, 1998 | May 10, 1999 | 1 | |
| Buddy Faro | September 25, 1998 | December 4, 1998 | 1 | |
| Martial Law | September 26, 1998 | May 13, 2000 | 2 | |
| To Have & to Hold | September 30, 1998 | December 9, 1998 | 1 | |
| Turks | January 21, 1999 | April 23, 1999 | 1 | |
| Sons of Thunder | March 9, 1999 | April 17, 1999 | 1 | |
| Judging Amy | September 19, 1999 | May 3, 2005 | 6 | |
| Family Law | September 20, 1999 | May 27, 2002 | 3 | |
| Now and Again | September 24, 1999 | May 5, 2000 | 1 | |
| City of Angels | January 16, 2000 | December 21, 2000 | 2 | |
| That's Life | October 1, 2000 | January 26, 2002 | 2 | |
| CSI: Crime Scene Investigation | October 6, 2000 | September 27, 2015 | 15 | |
| The Fugitive | October 6, 2000 | May 25, 2001 | 1 | |
| The District | October 7, 2000 | May 21, 2004 | 4 | |
| Kate Brasher | February 24, 2001 | April 14, 2001 | 1 | |
| Big Apple | March 1, 2001 | April 19, 2001 | 1 | |
| Wolf Lake | September 19, 2001 | October 24, 2001 | 1 | |
| The Education of Max Bickford | September 23, 2001 | June 2, 2002 | 1 | |
| The Guardian | September 25, 2001 | May 4, 2004 | 3 | |
| The Agency | September 27, 2001 | May 17, 2003 | 2 | |
| Citizen Baines | September 29, 2001 | November 3, 2001 | 1 | |
| First Monday | January 15, 2002 | May 3, 2002 | 1 | |
| CSI: Miami | September 23, 2002 | April 8, 2012 | 10 | |
| Presidio Med | September 24, 2002 | January 24, 2003 | 1 | |
| Without a Trace | September 26, 2002 | May 19, 2009 | 7 | |
| Hack | September 27, 2002 | March 13, 2004 | 2 | |
| Robbery Homicide Division | September 27, 2002 | December 7, 2002 | 1 | |
| Queens Supreme | January 10, 2003 | January 24, 2003 | 1 | |
| The Brotherhood of Poland, New Hampshire | September 24, 2003 | November 19, 2003 | 1 | |
| Joan of Arcadia | September 26, 2003 | April 22, 2005 | 2 | |
| Cold Case | September 28, 2003 | May 2, 2010 | 7 | |
| Century City | March 16, 2004 | March 30, 2004 | 1 | |
| CSI: NY | September 22, 2004 | February 22, 2013 | 9 | |
| Dr. Vegas | September 24, 2004 | October 29, 2004 | 1 | |
| Clubhouse | September 26, 2004 | November 6, 2004 | 1 | |
| NUMB3RS | January 23, 2005 | March 12, 2010 | 6 | |
| Elvis | May 8, 2005 | May 11, 2005 | Miniseries | 1 |
| Threshold | September 16, 2005 | November 22, 2005 | 1 | |
| Criminal Minds | September 22, 2005 | February 19, 2020 | Seasons 1–15 only Moved to Paramount+ for season 16–present | 15 |
| Ghost Whisperer | September 23, 2005 | May 21, 2010 | 5 | |
| Close to Home | October 4, 2005 | May 11, 2007 | 2 | |
| Love Monkey | January 17, 2006 | February 7, 2006 | 1 | |
| The Unit | March 7, 2006 | May 10, 2009 | 4 | |
| Smith | September 19, 2006 | October 3, 2006 | 1 | |
| Jericho | September 20, 2006 | March 25, 2008 | 2 | |
| Shark | September 21, 2006 | May 20, 2008 | 2 | |
| 3 lbs | November 14, 2006 | November 28, 2006 | 1 | |
| Cane | September 25, 2007 | December 18, 2007 | 1 | |
| Moonlight | September 28, 2007 | May 16, 2008 | 1 | |
| Viva Laughlin | October 18, 2007 | October 21, 2007 | 1 | |
| Comanche Moon | January 13, 2008 | January 16, 2008 | Miniseries | 1 |
| Swingtown | June 5, 2008 | September 5, 2008 | 1 | |
| Flashpoint | July 11, 2008 | August 19, 2011 | Seasons 1–4 only Moved to Ion Television for season 5 | 4 |
| The Mentalist | September 23, 2008 | February 18, 2015 | 7 | |
| The Ex List | October 3, 2008 | October 24, 2008 | 1 | |
| Eleventh Hour | October 9, 2008 | April 2, 2009 | 1 | |
| Harper's Island | April 9, 2009 | July 11, 2009 | 1 | |
| NCIS: Los Angeles | September 22, 2009 | May 21, 2023 | 14 | |
| The Good Wife | September 22, 2009 | May 8, 2016 | 7 | |
| Medium | September 25, 2009 | January 21, 2011 | Seasons 6–7 only Seasons 1–5 aired on NBC | 2 |
| Three Rivers | October 4, 2009 | July 3, 2010 | 1 | |
| Miami Medical | April 2, 2010 | July 2, 2010 | 1 | |
| Hawaii Five-0 | September 20, 2010 | April 3, 2020 | 10 | |
| The Defenders (2010) | September 22, 2010 | March 11, 2011 | 1 | |
| Blue Bloods | September 24, 2010 | December 13, 2024 | 14 | |
| Criminal Minds: Suspect Behavior | February 16, 2011 | May 25, 2011 | 1 | |
| CHAOS | April 1, 2011 | July 16, 2011 | 1 | |
| Unforgettable | September 20, 2011 | September 14, 2014 | Seasons 1–3 only Moved to A&E for season 4 | 3 |
| Person of Interest | September 22, 2011 | June 21, 2016 | 5 | |
| A Gifted Man | September 23, 2011 | March 2, 2012 | 1 | |
| NYC 22 | April 15, 2012 | August 11, 2012 | 1 | |
| Vegas | September 25, 2012 | May 10, 2013 | 1 | |
| Elementary | September 27, 2012 | August 15, 2019 | 7 | |
| Made in Jersey | September 28, 2012 | December 29, 2012 | 1 | |
| Golden Boy | February 26, 2013 | May 14, 2013 | 1 | |
| Under the Dome | June 24, 2013 | September 10, 2015 | 3 | |
| Hostages | September 23, 2013 | January 6, 2014 | 1 | |
| Intelligence | January 7, 2014 | March 31, 2014 | 1 | |
| Reckless | June 29, 2014 | September 13, 2014 | 1 | |
| Extant | July 9, 2014 | September 9, 2015 | 2 | |
| Madam Secretary | September 21, 2014 | December 8, 2019 | 6 | |
| Scorpion | September 22, 2014 | April 16, 2018 | 4 | |
| NCIS: New Orleans | September 23, 2014 | May 23, 2021 | 7 | |
| Stalker | October 1, 2014 | May 18, 2015 | 1 | |
| Battle Creek | March 1, 2015 | May 24, 2015 | 1 | |
| CSI: Cyber | March 4, 2015 | March 13, 2016 | 2 | |
| Zoo | June 30, 2015 | September 21, 2017 | 3 | |
| Limitless | September 22, 2015 | April 26, 2016 | 1 | |
| Code Black | September 30, 2015 | July 18, 2018 | 3 | |
| Supergirl | October 26, 2015 | April 18, 2016 | Season 1 only Moved to The CW for seasons 2–6 | 1 |
| Criminal Minds: Beyond Borders | March 16, 2016 | May 17, 2017 | 2 | |
| Rush Hour | March 31, 2016 | August 20, 2016 | 1 | |
| BrainDead | June 13, 2016 | September 11, 2016 | 1 | |
| American Gothic | June 22, 2016 | September 7, 2016 | 1 | |
| Bull | September 20, 2016 | May 26, 2022 | 6 | |
| MacGyver | September 23, 2016 | April 30, 2021 | 5 | |
| Pure Genius | October 27, 2016 | January 26, 2017 | 1 | |
| Ransom | January 1, 2017 | May 25, 2019 | 3 | |
| Training Day | February 2, 2017 | May 20, 2017 | 1 | |
| Doubt | February 15, 2017 | August 12, 2017 | 1 | |
| Salvation | July 12, 2017 | September 17, 2018 | 2 | |
| SEAL Team | September 27, 2017 | October 31, 2021 | Seasons 1–5A only Moved to Paramount+ for seasons 5B–7 | 5 |
| Wisdom of the Crowd | October 1, 2017 | January 14, 2018 | 1 | |
| S.W.A.T. | November 2, 2017 | May 16, 2025 | 8 | |
| Instinct | March 18, 2018 | August 25, 2019 | 2 | |
| Magnum P.I. (2018) | September 24, 2018 | May 6, 2022 | Seasons 1–4 only Moved to NBC for season 5 | 4 |
| God Friended Me | September 30, 2018 | April 26, 2020 | 2 | |
| The Code | April 9, 2019 | July 22, 2019 | 1 | |
| The Red Line | April 28, 2019 | May 19, 2019 | 1 | |
| Blood & Treasure | May 21, 2019 | August 6, 2019 | Season 1 only Moved to Paramount+ for season 2 | 1 |
| All Rise | September 23, 2019 | May 24, 2021 | Seasons 1–2 only Moved to Oprah Winfrey Network for season 3 | 2 |
| Evil | September 26, 2019 | January 30, 2020 | Season 1 only Moved to Paramount+ for seasons 2–4 | 1 |
| FBI: Most Wanted | January 7, 2020 | May 20, 2025 | 6 | |
| Tommy | February 6, 2020 | May 7, 2020 | 1 | |
| Manhunt: Deadly Games | September 21, 2020 | November 7, 2020 | 1 | |
| The Equalizer (2021) | February 7, 2021 | May 4, 2025 | 5 | |
| Clarice | February 11, 2021 | June 24, 2021 | 1 | |
| NCIS: Hawaiʻi | September 20, 2021 | May 6, 2024 | 3 | |
| FBI: International | September 21, 2021 | May 20, 2025 | 4 | |
| CSI: Vegas | October 6, 2021 | May 19, 2024 | 3 | |
| Good Sam | January 5, 2022 | May 4, 2022 | 1 | |
| So Help Me Todd | September 29, 2022 | May 16, 2024 | 2 | |
| East New York | October 2, 2022 | May 14, 2023 | 1 | |
| True Lies | March 1, 2023 | May 17, 2023 | 1 | |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| Detective's Wife | July 7, 1950 | September 29, 1950 | 1 | |
| The George Burns and Gracie Allen Show | October 12, 1950 | September 15, 1958 | 8 | |
| The Jack Benny Program | October 28, 1950 | April 21, 1964 | Seasons 1–14 only Moved to NBC for season 15 | 14 |
| I Love Lucy | October 15, 1951 | May 6, 1957 | 6 | |
| My Little Margie | May 16, 1952 | July 23, 1953 | Seasons 1–2 only Moved to NBC for seasons 3–4 | 2 |
| Private Secretary | February 1, 1953 | March 17, 1957 | 5 | |
| Willy | September 18, 1954 | June 16, 1955 | 1 | |
| Father Knows Best | October 3, 1954 | May 23, 1960 | Seasons 1, 5–6 only Moved to NBC for seasons 2–4 | 3 |
| December Bride | October 4, 1954 | May 7, 1959 | 5 | |
| Ethel and Albert | June 20, 1955 | September 26, 1955 | Season 3 only Seasons 1–2 aired on NBC Moved to ABC for season 4 | 1 |
| It's Always Jan | September 10, 1955 | April 28, 1956 | 1 | |
| The Phil Silvers Show | September 20, 1955 | September 11, 1959 | 4 | |
| The Bob Cummings Show | September 22, 1955 | June 6, 1957 | Seasons 2–3 only Seasons 1, 4–5 aired on NBC | 2 |
| The Honeymooners | October 4, 1955 | September 22, 1956 | 2 | |
| Hey, Jeannie! | September 8, 1956 | March 16, 1957 | Season 1 only Moved to first-run syndication for season 2 | 1 |
| Mr. Adams and Eve | January 4, 1957 | July 8, 1958 | 2 | |
| Bachelor Father | September 15, 1957 | June 7, 1959 | Seasons 1–2 only Moved to NBC for Seasons 3–4 and ABC for season 5 | 2 |
| The Eve Arden Show | September 17, 1957 | March 25, 1958 | 1 | |
| Leave It to Beaver | October 4, 1957 | July 16, 1958 | Season 1 only Moved to ABC for seasons 2–6 | 1 |
| The Danny Thomas Show | October 7, 1957 | April 27, 1964 | Seasons 5–11 only Seasons 1–4 aired on ABC | 7 |
| The Lucy–Desi Comedy Hour | November 28, 1957 | April 1, 1960 | 3 | |
| The Ann Sothern Show | October 6, 1958 | March 30, 1961 | 3 | |
| Hennesey | September 28, 1959 | September 17, 1962 | 3 | |
| The Many Loves of Dobie Gillis | September 29, 1959 | June 5, 1963 | 4 | |
| The Betty Hutton Show | October 1, 1959 | June 30, 1960 | 1 | |
| Dennis the Menace | October 4, 1959 | July 7, 1963 | 4 | |
| The Comedy Spot | June 28, 1960 | September 18, 1962 | Renamed Comedy Spotlight on July 25, 1961 | 3 |
| New Comedy Showcase | August 1, 1960 | September 19, 1960 | 1 | |
| Pete and Gladys | September 18, 1960 | September 10, 1962 | 2 | |
| The Tom Ewell Show | September 22, 1960 | May 23, 1961 | 1 | |
| The Andy Griffith Show | October 3, 1960 | April 1, 1968 | 8 | |
| My Sister Eileen | October 5, 1960 | April 12, 1961 | 1 | |
| Angel | October 6, 1960 | June 14, 1961 | 1 | |
| Bringing Up Buddy | October 10, 1960 | June 28, 1961 | 1 | |
| 'Way Out | March 31, 1961 | July 14, 1961 | 1 | |
| Ichabod and Me | September 26, 1961 | June 5, 1962 | 1 | |
| Father of the Bride | September 29, 1961 | May 25, 1962 | 1 | |
| Mister Ed | October 1, 1961 | February 6, 1966 | Seasons 2–6 only Season 1 aired in first-run syndication | 5 |
| The Dick Van Dyke Show | October 3, 1961 | June 1, 1966 | 5 | |
| Oh! Those Bells | March 8, 1962 | May 31, 1962 | 1 | |
| The Beverly Hillbillies | September 26, 1962 | March 23, 1971 | 9 | |
| The Real McCoys | September 30, 1962 | June 30, 1963 | Season 6 only Seasons 1–5 aired on ABC | 1 |
| The Lucy Show | October 1, 1962 | March 11, 1968 | 6 | |
| Vacation Playhouse | July 22, 1963 | August 28, 1967 | 5 | |
| Petticoat Junction | September 1, 1963 | April 4, 1970 | 7 | |
| The New Phil Silvers Show | September 28, 1963 | April 25, 1964 | 1 | |
| My Favorite Martian | September 29, 1963 | May 1, 1966 | 3 | |
| The Cara Williams Show | September 23, 1964 | April 21, 1965 | 1 | |
| The Munsters | September 24, 1964 | May 12, 1966 | 2 | |
| Gomer Pyle, U.S.M.C. | September 25, 1964 | May 2, 1969 | 5 | |
| Gilligan's Island | September 26, 1964 | April 17, 1967 | 3 | |
| The Joey Bishop Show | September 27, 1964 | March 30, 1965 | Season 4 only Seasons 1–3 aired on NBC | 1 |
| My Living Doll | September 27, 1964 | March 17, 1965 | 1 | |
| Hazel | September 13, 1965 | April 11, 1966 | Season 5 only Seasons 1–4 aired on NBC | 1 |
| Green Acres | September 15, 1965 | April 27, 1971 | 6 | |
| My Three Sons | September 16, 1965 | April 13, 1972 | Seasons 6–12 only Seasons 1–5 aired on ABC | 7 |
| Hogan's Heroes | September 17, 1965 | March 28, 1971 | 6 | |
| The Smothers Brothers Show | September 17, 1965 | April 22, 1966 | 1 | |
| It's About Time | September 11, 1966 | April 2, 1967 | 1 | |
| Family Affair | September 12, 1966 | March 4, 1971 | 5 | |
| Mr. Terrific | January 9, 1967 | August 28, 1967 | 1 | |
| Good Morning World | September 5, 1967 | March 19, 1968 | 1 | |
| He & She | September 6, 1967 | March 13, 1968 | 1 | |
| Premiere | July 1, 1968 | September 9, 1968 | 1 | |
| Here's Lucy | September 23, 1968 | March 18, 1974 | 6 | |
| Mayberry R.F.D. | September 23, 1968 | September 6, 1971 | 3 | |
| The Doris Day Show | September 24, 1968 | March 12, 1973 | 5 | |
| The Good Guys | September 25, 1968 | January 23, 1970 | 2 | |
| Blondie | September 26, 1968 | January 9, 1969 | 1 | |
| The Queen & I | January 16, 1969 | April 24, 1969 | 1 | |
| The Governor & J.J. | September 23, 1969 | December 30, 1970 | 2 | |
| Get Smart | September 26, 1969 | May 15, 1970 | Season 5 only Seasons 1–4 aired on NBC | 1 |
| To Rome with Love | September 28, 1969 | September 1, 1971 | 2 | |
| The Tim Conway Show | January 30, 1970 | June 19, 1970 | 1 | |
| Arnie | September 19, 1970 | March 6, 1972 | 2 | |
| The Mary Tyler Moore Show | September 19, 1970 | March 19, 1977 | 7 | |
| The New Andy Griffith Show | January 8, 1971 | May 21, 1971 | 1 | |
| All in the Family | January 12, 1971 | April 8, 1979 | 9 | |
| Comedy Playhouse | August 1, 1971 | September 5, 1971 | 1 | |
| The Chicago Teddy Bears | September 17, 1971 | December 10, 1971 | 1 | |
| The New Dick Van Dyke Show | September 18, 1971 | March 18, 1974 | 3 | |
| Funny Face | September 18, 1971 | December 11, 1971 | 1 | |
| Me and the Chimp | January 13, 1972 | April 27, 1972 | 1 | |
| The New Bill Cosby Show | September 11, 1972 | March 5, 1973 | 1 | |
| Maude | September 12, 1972 | April 22, 1978 | 6 | |
| The Bob Newhart Show | September 16, 1972 | April 1, 1978 | 6 | |
| Bridget Loves Bernie | September 16, 1972 | March 3, 1973 | 1 | |
| M*A*S*H | September 17, 1972 | February 28, 1983 | 11 | |
| The Sandy Duncan Show | September 17, 1972 | December 31, 1972 | 1 | |
| Anna and the King | September 17, 1972 | December 31, 1972 | 1 | |
| Calucci's Department | September 14, 1973 | December 28, 1973 | 1 | |
| Roll Out | October 5, 1973 | January 4, 1974 | 1 | |
| Good Times | February 8, 1974 | August 1, 1979 | 6 | |
| Rhoda | September 9, 1974 | December 9, 1978 | 5 | |
| Friends and Lovers | September 14, 1974 | January 4, 1975 | 1 | |
| The Jeffersons | January 18, 1975 | July 2, 1985 | 11 | |
| We'll Get By | March 14, 1975 | May 30, 1975 | 1 | |
| Joe and Sons | April 18, 1975 | January 13, 1976 | 1 | |
| Felix the Cat Live | June 6, 1975 | October 23, 1977 | 1 | |
| Big Eddie | August 23, 1975 | November 7, 1975 | 1 | |
| Phyllis | September 8, 1975 | March 13, 1977 | 2 | |
| Doc | September 13, 1975 | October 30, 1976 | 1 | |
| One Day at a Time | December 16, 1975 | May 28, 1984 | 9 | |
| Popi | January 20, 1976 | August 24, 1976 | 1 | |
| Alice | August 31, 1976 | March 19, 1985 | 9 | |
| All's Fair | September 20, 1976 | April 30, 1977 | 1 | |
| Ball Four | September 22, 1976 | October 27, 1976 | 1 | |
| Busting Loose | January 17, 1977 | November 16, 1977 | 1 | |
| Loves Me, Loves Me Not | March 20, 1977 | April 27, 1977 | 1 | |
| Szysznyk | August 1, 1977 | January 25, 1978 | 1 | |
| A Year at the Top | August 5, 1977 | September 2, 1977 | 1 | |
| The Betty White Show | September 22, 1977 | January 2, 1978 | 1 | |
| The Tony Randall Show | September 24, 1977 | March 25, 1978 | Season 2 only Season 1 aired on ABC | 1 |
| We've Got Each Other | October 1, 1977 | January 7, 1978 | 1 | |
| On Our Own | October 9, 1977 | August 27, 1978 | 1 | |
| Baby... I'm Back! | January 30, 1978 | April 24, 1978 | 1 | |
| Husbands, Wives & Lovers | March 10, 1978 | June 30, 1978 | 1 | |
| Another Day | April 8, 1978 | April 29, 1978 | 1 | |
| The Ted Knight Show | April 8, 1978 | May 13, 1978 | 1 | |
| Flying High | August 28, 1978 | January 23, 1979 | 1 | |
| WKRP in Cincinnati | September 18, 1978 | April 21, 1982 | 4 | |
| In the Beginning | September 20, 1978 | October 18, 1978 | 1 | |
| Billy | February 26, 1979 | April 28, 1979 | 1 | |
| Flatbush | February 26, 1979 | March 12, 1979 | 1 | |
| The Bad News Bears | March 24, 1979 | July 26, 1980 | 1 | |
| Hanging In | August 8, 1979 | August 29, 1980 | 1 | |
| Working Stiffs | September 15, 1979 | October 20, 1979 | 1 | |
| The Last Resort | September 19, 1979 | March 17, 1980 | 1 | |
| Struck by Lightning | September 19, 1979 | October 3, 1979 | 1 | |
| Archie Bunker's Place | September 23, 1979 | April 4, 1983 | 4 | |
| House Calls | December 17, 1979 | September 13, 1982 | 3 | |
| Flo | March 24, 1980 | July 21, 1981 | 1 | |
| Ladies' Man (1980) | October 27, 1980 | February 21, 1981 | 1 | |
| Private Benjamin | April 6, 1981 | January 10, 1983 | 3 | |
| The Two of Us | April 6, 1981 | February 24, 1982 | 2 | |
| Checking In | April 9, 1981 | April 30, 1981 | 1 | |
| Park Place | April 9, 1981 | April 30, 1981 | 1 | |
| Mr. Merlin | October 7, 1981 | March 22, 1982 | 1 | |
| Making the Grade | April 5, 1982 | May 10, 1982 | 1 | |
| Report to Murphy | April 5, 1982 | May 31, 1982 | 1 | |
| Filthy Rich | August 9, 1982 | July 15, 1983 | 1 | |
| Gloria | September 26, 1982 | April 10, 1983 | 1 | |
| Square Pegs | September 27, 1982 | March 7, 1983 | 1 | |
| Newhart | October 25, 1982 | May 21, 1990 | 8 | |
| Ace Crawford, Private Eye | March 15, 1983 | April 12, 1983 | 1 | |
| Gun Shy | March 15, 1983 | April 19, 1983 | 1 | |
| Goodnight, Beantown | April 2, 1983 | January 18, 1984 | 1 | |
| AfterMASH | September 26, 1983 | May 31, 1985 | 2 | |
| Domestic Life | January 4, 1984 | February 1, 1984 | 1 | |
| Empire | January 4, 1984 | April 15, 1984 | 1 | |
| Maggie Briggs | March 4, 1984 | April 15, 1984 | 1 | |
| Mama Malone | March 7, 1984 | July 21, 1984 | 1 | |
| Kate & Allie | March 19, 1984 | May 22, 1989 | 6 | |
| E/R | September 16, 1984 | February 27, 1985 | 1 | |
| Charles in Charge | October 3, 1984 | April 3, 1985 | Season 1 only Moved to first-run syndication for seasons 2–5 | 1 |
| Dreams | October 3, 1984 | October 31, 1984 | 1 | |
| The Lucie Arnaz Show | April 2, 1985 | June 11, 1986 | 1 | |
| Charlie & Co. | September 18, 1985 | May 16, 1986 | 1 | |
| George Burns Comedy Week | September 18, 1985 | December 25, 1985 | 1 | |
| Stir Crazy | September 18, 1985 | January 7, 1986 | 1 | |
| Foley Square | December 11, 1985 | April 8, 1986 | 1 | |
| Mary | December 11, 1985 | April 8, 1986 | 1 | |
| Fast Times | March 5, 1986 | April 23, 1986 | 1 | |
| Tough Cookies | March 5, 1986 | April 23, 1986 | 1 | |
| Leo & Liz in Beverly Hills | April 25, 1986 | June 6, 1986 | 1 | |
| Together We Stand | September 22, 1986 | April 24, 1987 | Renamed Nothing Is Easy on February 8, 1987 | 1 |
| Designing Women | September 29, 1986 | May 24, 1993 | 7 | |
| Better Days | October 1, 1986 | October 29, 1986 | 1 | |
| My Sister Sam | October 6, 1986 | April 12, 1988 | 2 | |
| The Cavanaughs | December 1, 1986 | July 27, 1989 | 3 | |
| The Popcorn Kid | March 23, 1987 | April 24, 1987 | 1 | |
| Roxie | April 1, 1987 | April 8, 1987 | 1 | |
| Take Five | April 1, 1987 | April 8, 1987 | 1 | |
| CBS Summer Playhouse | June 12, 1987 | August 22, 1989 | 3 | |
| Frank's Place | September 14, 1987 | March 22, 1988 | 1 | |
| Everything's Relative | October 3, 1987 | November 7, 1987 | 1 | |
| Eisenhower and Lutz | March 14, 1988 | June 20, 1988 | 1 | |
| Coming of Age | March 15, 1988 | July 27, 1989 | 1 | |
| Trial and Error | March 15, 1988 | March 29, 1988 | 1 | |
| Annie McGuire | October 26, 1988 | December 28, 1988 | 1 | |
| The Van Dyke Show | October 26, 1988 | December 7, 1988 | 1 | |
| Raising Miranda | November 5, 1988 | December 31, 1988 | 1 | |
| Murphy Brown | November 14, 1988 | December 20, 2018 | 11 | |
| Heartland | March 20, 1989 | June 12, 1989 | 1 | |
| Live-In | March 20, 1989 | May 29, 1989 | 1 | |
| Doctor Doctor | June 12, 1989 | July 6, 1991 | 3 | |
| Major Dad | September 17, 1989 | April 16, 1993 | 4 | |
| The Famous Teddy Z | September 18, 1989 | May 12, 1990 | 1 | |
| The People Next Door | September 18, 1989 | October 16, 1989 | 1 | |
| City | January 29, 1990 | June 8, 1990 | 1 | |
| His & Hers | March 5, 1990 | August 22, 1990 | 1 | |
| Normal Life | March 21, 1990 | July 18, 1990 | 1 | |
| Sydney | March 21, 1990 | June 25, 1990 | 1 | |
| Bagdad Cafe | March 30, 1990 | July 27, 1991 | 1 | |
| Sugar and Spice | March 30, 1990 | May 25, 1990 | 1 | |
| Lenny | September 10, 1990 | March 9, 1991 | 1 | |
| Uncle Buck | September 10, 1990 | March 9, 1991 | 1 | |
| The Family Man | September 11, 1990 | July 17, 1991 | 1 | |
| The Hogan Family | September 15, 1990 | July 20, 1991 | Season 6 only Seasons 1–5 aired on NBC | 1 |
| Evening Shade | September 21, 1990 | May 23, 1994 | 4 | |
| You Take the Kids | December 15, 1990 | January 12, 1991 | 1 | |
| Sunday Dinner | June 2, 1991 | July 7, 1991 | 1 | |
| Good Sports | January 10, 1991 | July 13, 1991 | 1 | |
| The Royal Family | September 18, 1991 | May 13, 1992 | 1 | |
| Teech | September 18, 1991 | October 16, 1991 | 1 | |
| Brooklyn Bridge | September 20, 1991 | August 6, 1993 | 2 | |
| Princesses | September 27, 1991 | October 25, 1991 | 1 | |
| Davis Rules | December 30, 1991 | May 13, 1992 | Season 2 only Season 1 aired on ABC | 1 |
| Grapevine (1992) | June 15, 1992 | July 27, 1992 | 1 | |
| Frannie's Turn | September 13, 1992 | October 10, 1992 | 1 | |
| Hearts Afire | September 14, 1992 | February 1, 1995 | 3 | |
| Bob | September 18, 1992 | December 27, 1993 | 1 | |
| The Golden Palace | September 18, 1992 | May 14, 1993 | 1 | |
| Love & War | September 21, 1992 | February 1, 1995 | 3 | |
| Good Advice | April 2, 1993 | September 6, 1994 | 2 | |
| A League of Their Own | April 10, 1993 | August 13, 1993 | 1 | |
| Dudley | April 16, 1993 | May 14, 1993 | 1 | |
| The Boys | August 18, 1993 | September 17, 1993 | 1 | |
| The Building | August 20, 1993 | September 17, 1993 | 1 | |
| The Trouble with Larry | August 25, 1993 | September 8, 1993 | 1 | |
| It Had to Be You | September 19, 1993 | October 15, 1993 | 1 | |
| Dave's World | September 20, 1993 | June 20, 1997 | 4 | |
| Family Album | September 24, 1993 | November 12, 1993 | 1 | |
| The Nanny | November 3, 1993 | June 23, 1999 | 6 | |
| Tom | March 2, 1994 | June 13, 1994 | 1 | |
| 704 Hauser | April 11, 1994 | May 9, 1994 | 1 | |
| Muddling Through | July 9, 1994 | September 7, 1994 | 1 | |
| The Boys Are Back | September 11, 1994 | January 28, 1995 | 1 | |
| Daddy's Girls | September 21, 1994 | October 12, 1994 | 1 | |
| The 5 Mrs. Buchanans | September 24, 1994 | March 25, 1995 | 1 | |
| Cybill | January 2, 1995 | July 13, 1998 | 4 | |
| Double Rush | January 4, 1995 | April 12, 1995 | 1 | |
| Women of the House | January 4, 1995 | August 18, 1995 | The first eight episodes only The remaining five episodes were released on Lifetime | 1 |
| The George Wendt Show | March 8, 1995 | April 12, 1995 | 1 | |
| Bless This House | September 11, 1995 | January 17, 1996 | 1 | |
| Almost Perfect | September 17, 1995 | October 30, 1996 | 1 | |
| Can't Hurry Love | September 18, 1995 | February 26, 1996 | 1 | |
| If Not for You | September 18, 1995 | October 9, 1995 | 1 | |
| Bonnie | September 22, 1995 | April 7, 1996 | 1 | |
| High Society | October 30, 1995 | February 26, 1996 | 1 | |
| Everybody Loves Raymond | September 13, 1996 | May 16, 2005 | 9 | |
| Cosby | September 16, 1996 | April 28, 2000 | 4 | |
| Pearl | September 16, 1996 | June 25, 1997 | 1 | |
| Ink | October 21, 1996 | May 19, 1997 | 1 | |
| Temporarily Yours | March 5, 1997 | April 9, 1997 | 1 | |
| George and Leo | September 15, 1997 | March 16, 1998 | 1 | |
| The Gregory Hines Show | September 15, 1997 | February 27, 1998 | 1 | |
| Family Matters | September 19, 1997 | July 17, 1998 | Season 9 only Seasons 1–8 aired on ABC | 1 |
| Meego | September 19, 1997 | October 24, 1997 | 1 | |
| Step by Step | September 19, 1997 | June 26, 1998 | Season 7 only Seasons 1–6 aired on ABC | 1 |
| Style & Substance | January 5, 1998 | September 2, 1998 | 1 | |
| The Closer | February 23, 1998 | May 4, 1998 | 1 | |
| The Simple Life | June 3, 1998 | July 8, 1998 | 1 | |
| The Brian Benben Show | September 21, 1998 | October 12, 1998 | 1 | |
| The King of Queens | September 21, 1998 | May 14, 2007 | 9 | |
| Maggie Winters | September 30, 1998 | February 3, 1999 | 1 | |
| Becker | November 2, 1998 | January 28, 2004 | 6 | |
| Payne | March 15, 1999 | April 28, 1999 | 1 | |
| Ladies Man (1990) | September 20, 1999 | June 27, 2001 | 2 | |
| Work with Me | September 29, 1999 | October 20, 1999 | 1 | |
| Love & Money | October 8, 1999 | July 18, 2000 | 1 | |
| Grapevine (2000) | February 28, 2000 | March 27, 2000 | 1 | |
| Yes, Dear | October 2, 2000 | February 15, 2006 | 6 | |
| Bette | October 11, 2000 | March 7, 2001 | 1 | |
| Welcome to New York | October 11, 2000 | January 17, 2001 | 1 | |
| Some of My Best Friends | February 28, 2001 | April 1, 2001 | 1 | |
| The Ellen Show | September 24, 2001 | January 11, 2002 | 1 | |
| Baby Bob | March 18, 2002 | June 20, 2003 | 2 | |
| Still Standing | September 30, 2002 | March 8, 2006 | 4 | |
| My Big Fat Greek Life | February 24, 2003 | April 13, 2003 | 1 | |
| Charlie Lawrence | June 15, 2003 | June 22, 2003 | 1 | |
| Two and a Half Men | September 22, 2003 | February 19, 2015 | 12 | |
| The Stones | March 17, 2004 | March 31, 2004 | 1 | |
| Listen Up | September 20, 2004 | April 25, 2005 | 1 | |
| Center of the Universe | October 27, 2004 | January 19, 2005 | 1 | |
| How I Met Your Mother | September 19, 2005 | March 31, 2014 | 9 | |
| Out of Practice | September 19, 2005 | March 29, 2006 | 1 | |
| Courting Alex | January 23, 2006 | March 29, 2006 | 1 | |
| The New Adventures of Old Christine | March 13, 2006 | May 12, 2010 | 5 | |
| The Class | September 18, 2006 | March 5, 2007 | 1 | |
| Rules of Engagement | February 5, 2007 | May 20, 2013 | 7 | |
| The Big Bang Theory | September 24, 2007 | May 16, 2019 | 12 | |
| Welcome to The Captain | February 4, 2008 | March 3, 2008 | 1 | |
| Worst Week | September 22, 2008 | June 6, 2009 | 1 | |
| Gary Unmarried | September 24, 2008 | March 17, 2010 | 2 | |
| Accidentally on Purpose | September 21, 2009 | April 21, 2010 | 1 | |
| Mike & Molly | September 20, 2010 | May 16, 2016 | 6 | |
| $#*! My Dad Says | September 23, 2010 | February 17, 2011 | 1 | |
| Mad Love | February 14, 2011 | May 16, 2011 | 1 | |
| 2 Broke Girls | September 19, 2011 | April 17, 2017 | 6 | |
| How to Be a Gentleman | September 29, 2011 | June 23, 2012 | 1 | |
| Rob | January 12, 2012 | March 1, 2012 | 1 | |
| Partners | September 24, 2012 | November 12, 2012 | 1 | |
| Mom | September 23, 2013 | May 13, 2021 | 8 | |
| The Crazy Ones | September 26, 2013 | April 17, 2014 | 1 | |
| We Are Men | September 30, 2013 | October 14, 2013 | 1 | |
| The Millers | October 3, 2013 | July 18, 2015 | 2 | |
| Friends with Better Lives | March 31, 2014 | May 26, 2014 | 1 | |
| Bad Teacher | April 24, 2014 | July 26, 2014 | 1 | |
| The McCarthys | October 30, 2014 | July 11, 2015 | 1 | |
| The Odd Couple | February 19, 2015 | January 30, 2017 | 3 | |
| Life in Pieces | September 21, 2015 | June 27, 2019 | 4 | |
| Angel from Hell | January 7, 2016 | July 23, 2016 | 1 | |
| Kevin Can Wait | September 19, 2016 | May 7, 2018 | 2 | |
| Man with a Plan | October 24, 2016 | June 11, 2020 | 4 | |
| The Great Indoors | October 27, 2016 | May 8, 2017 | 1 | |
| Superior Donuts | February 2, 2017 | May 14, 2018 | 2 | |
| Me, Myself & I | September 25, 2017 | July 21, 2018 | 1 | |
| Young Sheldon | September 25, 2017 | May 16, 2024 | 7 | |
| 9JKL | October 2, 2017 | February 5, 2018 | 1 | |
| Living Biblically | February 26, 2018 | July 21, 2018 | 1 | |
| Happy Together | October 1, 2018 | January 14, 2019 | 1 | |
| Fam | January 10, 2019 | April 11, 2019 | 1 | |
| Bob Hearts Abishola | September 23, 2019 | May 6, 2024 | 5 | |
| Carol's Second Act | September 26, 2019 | March 12, 2020 | 1 | |
| The Unicorn | September 26, 2019 | March 18, 2021 | 2 | |
| Broke | April 2, 2020 | June 25, 2020 | 1 | |
| B Positive | November 5, 2020 | March 10, 2022 | 2 | |
| United States of Al | April 1, 2021 | May 19, 2022 | 2 | |
| How We Roll | March 31, 2022 | May 19, 2022 | 1 | |
| Poppa's House | October 21, 2024 | April 28, 2025 | 1 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| Where's Huddles? | July 2, 1970 | September 1, 1970 | 1 | |
| Fish Police | February 28, 1992 | March 13, 1992 | 1 | |
| Family Dog | June 23, 1993 | July 28, 1993 | 1 | |
| Creature Comforts | June 4, 2007 | June 18, 2007 | 1 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| The Alvin Show | October 4, 1961 | March 28, 1962 | 1 | |
| Tom and Jerry | September 25, 1965 | September 17, 1972 | 1 | |
| Famous Classic Tales | November 1, 1970 | November 23, 1984 | 1 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| The FBI Declassified | October 6, 2020 | August 18, 2021 | 1 | |
| FBI True | November 7, 2023 | February 14, 2024 | Season 4 only Seasons 1–3, 5–present are released on Paramount+ | 1 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| What's My Line? | February 2, 1950 | September 3, 1967 | 25 | |
| Beat the Clock | March 23, 1950 | September 16, 1958 | Seasons 1–8 only Moved to ABC for seasons 9–11 | 8 |
| I've Got a Secret (1952) | June 19, 1952 | April 3, 1967 | 15 | |
| Bank on the Stars | June 20, 1953 | August 8, 1953 | Season 1 only Moved to NBC for season 2 | 1 |
| Name That Tune | July 6, 1953 | October 19, 1959 | Seasons 3–10 only Seasons 1–2 aired on NBC | 8 |
| To Tell the Truth | December 18, 1956 | September 6, 1968 | 11 | |
| For Love or Money | May 29, 1958 | January 30, 1959 | 1 | |
| College Bowl | 1959 | 1963 | Seasons 3–6 only Seasons 1–2, 7–14 aired on NBC | 4 |
| Password | October 2, 1961 | September 15, 1967 | Seasons 1–5 only Moved to ABC for seasons 6–9 | 5 |
| The Amateur's Guide to Love | March 27, 1972 | June 23, 1972 | 1 | |
| Gambit | September 4, 1972 | December 10, 1976 | 5 | |
| The Joker's Wild | September 4, 1972 | June 13, 1975 | Seasons 1–3 only Moved to first-run syndication for seasons 4–12 | 3 |
| The $10,000 Pyramid | March 26, 1973 | March 29, 1974 | Season 1 only Moved to ABC for seasons 2–3 | 1 |
| Hollywood's Talking | March 26, 1973 | June 22, 1973 | 1 | |
| Match Game | July 2, 1973 | April 20, 1979 | Seasons 8–13 only Seasons 1–7 aired on NBC | 6 |
| Tattletales (1974) | February 18, 1974 | March 31, 1978 | 5 | |
| Now You See It (1974) | April 1, 1974 | June 13, 1975 | 2 | |
| Musical Chairs | June 16, 1975 | October 31, 1975 | 1 | |
| Spin-Off | June 16, 1975 | September 5, 1975 | 1 | |
| Give-n-Take | September 8, 1975 | November 28, 1975 | 1 | |
| I've Got a Secret (1976) | June 15, 1976 | July 6, 1976 | 1 | |
| Double Dare | December 13, 1976 | April 29, 1977 | 1 | |
| Pass the Buck | April 3, 1978 | June 30, 1978 | 1 | |
| Tic-Tac-Dough | July 3, 1978 | September 1, 1978 | Season 5 only Seasons 1–4 aired on NBC Moved to first-run syndication for seasons 8–13 | 1 |
| Whew! | April 23, 1979 | May 30, 1980 | 2 | |
| All-New Beat the Clock | September 17, 1979 | February 1, 1980 | Renamed to The All-New All-Star Beat The Clock on On November 5, 1979 | 2 |
| Tattletales (1982) | January 18, 1982 | June 1, 1984 | ||
| The New $25,000 Pyramid | September 20, 1982 | September 2, 1988 | 6 | |
| Child's Play | September 20, 1982 | September 16, 1983 | 2 | |
| Press Your Luck | September 19, 1983 | September 26, 1986 | 4 | |
| Body Language | June 4, 1984 | January 3, 1986 | 2 | |
| Card Sharks | January 6, 1986 | March 31, 1989 | Seasons 4–7 only Seasons 1–3 aired on NBC Moved to first-run syndication for season 8 | 4 |
| Blackout | January 4, 1988 | April 1, 1988 | 1 | |
| Family Feud | July 4, 1988 | March 25, 1993 | Seasons 18–23 only Seasons 1–10 aired on ABC Seasons 11–18, 24–30 aired in first-run syndication | 6 |
| Now You See It (1989) | April 3, 1989 | July 14, 1989 | 1 | |
| Wheel of Fortune | July 17, 1989 | January 11, 1991 | Seasons 15–16 only Seasons 1–14, 17 aired on NBC Moved to first-run syndication for season 18–present | 2 |
| The Hollywood Game | June 19, 1992 | July 10, 1992 | 1 | |
| Wheel 2000 | September 13, 1997 | February 7, 1998 | Also known as Wheel of Fortune 2000 | 1 |
| Winning Lines | January 8, 2000 | February 18, 2000 | 1 | |
| Gameshow Marathon | May 31, 2006 | June 29, 2006 | 1 | |
| Power of 10 | August 7, 2007 | January 23, 2008 | 1 | |
| Million Dollar Password | June 1, 2008 | June 14, 2009 | 2 | |
| Game Show in My Head | January 3, 2009 | January 24, 2009 | 1 | |
| Candy Crush | July 8, 2017 | September 2, 2017 | 1 | |
| TKO: Total Knock Out | July 11, 2018 | September 21, 2018 | 1 | |
| Million Dollar Mile | March 27, 2019 | August 3, 2019 | 1 | |
| Game On! | May 27, 2020 | July 22, 2020 | 1 | |
| Superfan | August 9, 2023 | September 20, 2023 | 1 | |
| Loteria Loca | October 2, 2023 | December 24, 2023 | 1 | |
| After Midnight | January 17, 2024 | June 13, 2025 | 2 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| Candid Camera (1960) | September 10, 1960 | November 11, 1967 | 7 | |
| That's My Line | August 9, 1980 | April 11, 1981 | 2 | |
| Top Cops | August 18, 1990 | December 8, 1993 | 4 | |
| Kids Say the Darndest Things (1997) | May 16, 1997 | June 23, 2000 | 3 | |
| Unsolved Mysteries | November 13, 1997 | June 11, 1999 | Seasons 10–11 only Seasons 1–9 aired on NBC Moved to Lifetime for seasons 12–13 | 2 |
| Candid Camera (1998) | February 27, 1998 | July 21, 2001 | Seasons 1–3 only Moved to Pac TV for seasons 4–6 | 3 |
| Cupid | July 9, 2003 | September 17, 2003 | 1 | |
| The Will | January 8, 2005 | 1 | ||
| Fire Me...Please | June 7, 2005 | July 5, 2005 | 1 | |
| The Cut | June 9, 2005 | September 7, 2005 | 1 | |
| Rock Star | July 11, 2005 | September 13, 2006 | 2 | |
| Tuesday Night Book Club | June 13, 2006 | June 21, 2006 | 1 | |
| Armed & Famous | January 10, 2007 | January 24, 2007 | 1 | |
| Pirate Master | May 31, 2007 | August 28, 2007 | 1 | |
| Kid Nation | September 19, 2007 | December 12, 2007 | 1 | |
| Greatest American Dog | July 10, 2008 | September 10, 2008 | 1 | |
| There Goes the Neighborhood | August 9, 2009 | September 13, 2009 | 1 | |
| Undercover Boss | February 7, 2010 | April 8, 2022 | 11 | |
| Live to Dance | January 4, 2011 | February 9, 2011 | 1 | |
| Same Name | July 24, 2011 | August 14, 2011 | 1 | |
| Dogs in the City | May 30, 2012 | July 11, 2012 | 1 | |
| 3 | July 26, 2012 | July 29, 2012 | 1 | |
| The Job | February 8, 2013 | February 15, 2013 | 1 | |
| Brooklyn DA | May 28, 2013 | July 6, 2013 | 1 | |
| The American Baking Competition | May 29, 2013 | July 10, 2013 | 1 | |
| The Briefcase | May 27, 2015 | June 26, 2015 | 1 | |
| Hunted | January 22, 2017 | March 1, 2017 | 1 | |
| Celebrity Big Brother | February 7, 2018 | February 23, 2022 | 3 | |
| Celebrity Undercover Boss | May 11, 2018 | June 22, 2018 | 1 | |
| Whistleblower | July 13, 2018 | June 28, 2019 | 2 | |
| The World's Best | February 3, 2019 | March 13, 2019 | 1 | |
| Love Island | July 9, 2019 | August 15, 2021 | Seasons 1–3 only Moved to Peacock for season 4–present | 3 |
| Tough as Nails | July 8, 2020 | July 30, 2023 | 5 | |
| Kids Say the Darndest Things (2019) | May 5, 2021 | May 23, 2021 | Season 2 only Season 1 aired on ABC | 1 |
| House Calls with Dr. Phil | August 18, 2021 | September 15, 2021 | 1 | |
| Beyond the Edge | March 16, 2022 | May 18, 2022 | 1 | |
| Come Dance with Me | April 15, 2022 | June 24, 2022 | 1 | |
| The Challenge: USA | July 6, 2022 | October 19, 2023 | 2 | |
| The Real Love Boat | October 5, 2022 | October 26, 2022 | The first four episodes only The remaining eight episodes were released on Paramount+ | 1 |
| Buddy Games | September 14, 2023 | November 2, 2023 | 1 | |
| Big Brother Reindeer Games | December 11, 2023 | December 21, 2023 | 1 | |
| The Summit | September 29, 2024 | December 4, 2024 | 1 | |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| The Ed Sullivan Show | June 20, 1948 | June 6, 1971 | 24 | |
| Arthur Godfrey's Talent Scouts | December 6, 1948 | January 1, 1958 | 10 | |
| Arthur Godfrey and His Friends | January 12, 1949 | April 28, 1959 | 10 | |
| Joey Faye's Frolics | April 5, 1950 | April 12, 1950 | 1 | |
| The Garry Moore Show | June 26, 1950 | January 8, 1967 | 16 | |
| The Jackie Gleason Show (1952) | September 20, 1952 | June 22, 1957 | 4 | |
| The Larry Storch Show | July 11, 1953 | September 12, 1953 | 1 | |
| The Red Skelton Show | September 22, 1953 | April 17, 1970 | Seasons 3–19 only Seasons 1–2, 20 aired on NBC | 17 |
| The Jackie Gleason Show (1961) | February 3, 1961 | March 24, 1961 | 1 | |
| The Danny Kaye Show | September 25, 1963 | June 28, 1967 | 4 | |
| The Entertainers | September 25, 1964 | March 27, 1965 | 1 | |
| The Smothers Brothers Comedy Hour | September 5, 1967 | June 8, 1969 | 3 | |
| The Carol Burnett Show | September 11, 1967 | March 29, 1978 | 11 | |
| Hee Haw | June 15, 1969 | February 23, 1971 | Seasons 1–2 only Seasons 3–26 aired in first-run syndication | 2 |
| The Merv Griffin Show | August 18, 1969 | February 11, 1972 | Seasons 6–8 only Season 1 aired on NBC. Seasons 2–5, 9–23 aired in first-run syndication | 3 |
| The Tim Conway Comedy Hour | September 20, 1970 | December 13, 1970 | 1 | |
| The Sonny & Cher Comedy Hour | August 1, 1971 | May 29, 1974 | 4 | |
| Tony Orlando and Dawn | July 3, 1974 | December 28, 1976 | Renamed The Tony Orlando and Dawn Rainbow Hour on September 21, 1976 | 3 |
| Cher | February 16, 1975 | January 4, 1976 | 2 | |
| The Sonny and Cher Show | February 1, 1976 | March 11, 1977 | 2 | |
| The Jacksons | June 16, 1976 | March 9, 1977 | 1 | |
| Mary | September 24, 1978 | October 8, 1978 | 1 | |
| The Mary Tyler Moore Hour | March 4, 1979 | June 10, 1979 | 1 | |
| The Tim Conway Show | March 22, 1980 | March 7, 1981 | 2 | |
| The Pat Sajak Show | January 9, 1989 | April 13, 1990 | 1 | |
| Late Show with David Letterman | August 30, 1993 | May 20, 2015 | 23 | |
| The Late Late Show with Tom Snyder | January 9, 1995 | March 26, 1999 | 5 | |
| The Late Late Show with Craig Kilborn | March 25, 1999 | August 27, 2004 | 6 | |
| Star Search | January 8, 2003 | March 13, 2004 | Season 13 only Seasons 1–12 aired in first-run syndication | 1 |
| The Late Late Show with Craig Ferguson | January 3, 2005 | December 19, 2014 | 10 | |
| The Talk | October 18, 2010 | December 20, 2024 | 15 | |
| The Late Late Show with James Corden | March 23, 2015 | April 27, 2023 | 9 |
| Title | Premiere date | Finale | Notes | Seasons |
|---|---|---|---|---|
| The First Hundred Years | December 4, 1950 | June 27, 1952 | 2 | |
| The Egg and I | September 3, 1951 | August 1, 1952 | 1 | |
| Search for Tomorrow | September 3, 1951 | March 26, 1982 | Seasons 1–30 only Moved to NBC for seasons 31–35 | 30 |
| Love of Life | September 24, 1951 | February 1, 1980 | 29 | |
| Guiding Light | June 30, 1952 | September 18, 2009 | 57 | |
| Valiant Lady | October 12, 1953 | August 16, 1957 | 4 | |
| The Brighter Day | January 4, 1954 | September 28, 1962 | 8 | |
| The Secret Storm | February 1, 1954 | February 8, 1974 | 20 | |
| Woman with a Past | February 1, 1954 | July 2, 1954 | 1 | |
| Portia Faces Life | April 5, 1954 | July 1, 1955 | 2 | |
| The Road of Life | December 13, 1954 | July 1, 1955 | 1 | |
| As the World Turns | April 2, 1956 | September 17, 2010 | 54 | |
| The Edge of Night | April 2, 1956 | November 28, 1975 | Seasons 1–19 only Moved to ABC for seasons 20–28 | 19 |
| Full Circle | June 27, 1960 | March 10, 1961 | 1 | |
| The Clear Horizon | July 11, 1960 | June 15, 1962 | 2 | |
| Love Is a Many Splendored Thing | September 18, 1967 | March 23, 1973 | 6 | |
| Where the Heart Is | September 8, 1969 | March 23, 1973 | 4 | |
| Capitol | March 29, 1982 | March 20, 1987 | 5 |