OR10A6

OR10A6
Identifiers
Aliases	OR10A6 , OR11-96, olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)
External IDs	MGI: 3030353 HomoloGene: 17186 GeneCards: OR10A6
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 7,924,592 bp [1] End 7,931,268 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 108,492,668 bp [2] End 108,493,627 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen ascending aorta prostate tibial nerve n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component membrane plasma membrane integral component of membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390093 277935 Ensembl ENSG00000279000 ENSG00000280899 ENSG00000276451 ENSMUSG00000066239 UniProt Q8NH74 n/a RefSeq (mRNA) NM_001004461 NM_001389574 NM_207160 RefSeq (protein) NP_001004461 n/a Location (UCSC) Chr 11: 7.92 – 7.93 Mb Chr 7: 108.49 – 108.49 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10A6 is a protein that in humans is encoded by the OR10A6 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G-protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000280899, ENSG00000276451 GRCh38: Ensembl release 89: ENSG00000279000, ENSG00000280899, ENSG00000276451 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000066239 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10A6 olfactory receptor, family 10, subfamily A, member 6".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10A6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.