OR4K1

OR4K1
Identifiers
Aliases	OR4K1 , OR14-19, olfactory receptor family 4 subfamily K member 1
External IDs	MGI: 3030562 HomoloGene: 74224 GeneCards: OR4K1
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 19,930,917 bp [1] End 19,936,757 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 C1 Start 50,133,758 bp [2] End 50,142,680 bp [2]
Gene ontology Molecular function • transmembrane signaling receptor activity • olfactory receptor activity • signal transducer activity • G-protein coupled receptor activity Cellular component • membrane • integral component of membrane • cell membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79544	258039
Ensembl	ENSG00000155249	ENSMUSG00000050030
UniProt	Q8NGD4	Q7TRM6
RefSeq (mRNA)	NM_001004063	NM_001011809
RefSeq (protein)	NP_001004063	NP_001011809
Location (UCSC)	Chr 14: 19.93 – 19.94 Mb	Chr 14: 50.13 – 50.14 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4K1 is a protein that in humans is encoded by the OR4K1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000155249 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050030 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4K1 olfactory receptor, family 4, subfamily K, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.