OR4X2

OR4X2
Identifiers
Aliases	OR4X2 , OR11-105, olfactory receptor family 4 subfamily X member 2 (gene/pseudogene), olfactory receptor family 4 subfamily X member 2
External IDs	HomoloGene: 103824 GeneCards: OR4X2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p11.2 Start 48,245,104 bp [1] End 48,246,015 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 119764 n/a Ensembl ENSG00000172208 n/a UniProt Q8NGF9 n/a RefSeq (mRNA) NM_001004727 n/a RefSeq (protein) NP_001004727 n/a Location (UCSC) Chr 11: 48.25 – 48.25 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 4X2 is a protein that in humans is encoded by the OR4X2 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172208 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR4X2 olfactory receptor, family 4, subfamily X, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4X2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.