OR1L4

OR1L4
Identifiers
Aliases	OR1L4 , OR1L5, OR9-29, OR9-E, OST046, olfactory receptor family 1 subfamily L member 4
External IDs	HomoloGene: 133031 GeneCards: OR1L4
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,723,990 bp [1] End 122,724,925 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Achilles tendon corpus callosum right uterine tube n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component membrane plasma membrane integral component of membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 254973 n/a Ensembl ENSG00000136939 n/a UniProt Q8NGR5 n/a RefSeq (mRNA) NM_001005235 n/a RefSeq (protein) NP_001005235 n/a Location (UCSC) Chr 9: 122.72 – 122.72 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 1L4 is a protein that in humans is encoded by the OR1L4 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000136939 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR1L4 olfactory receptor, family 1, subfamily L, member 4".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR1L4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.