OR8G5

OR8G5
Identifiers
Aliases	OR8G5 , OR11-298, OR8G5P, OR8G6, olfactory receptor family 8 subfamily G member 5
External IDs	MGI: 3030769 HomoloGene: 133683 GeneCards: OR8G5
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.2 Start 124,256,376 bp [1] End 124,266,224 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.1 Start 38,905,267 bp [2] End 38,910,979 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta duodenum transverse colon urinary bladder upper lobe of left lung subcutaneous adipose tissue blood nervous system skin of abdomen tibial nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219865 258741 Ensembl ENSG00000255298 ENSMUSG00000059595 UniProt Q8NG78 Q8VG16 RefSeq (mRNA) NM_001005198 NM_146746 RefSeq (protein) NP_001005198 NP_666957 Location (UCSC) Chr 11: 124.26 – 124.27 Mb Chr 9: 38.91 – 38.91 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8G5 is a protein that in humans is encoded by the OR8G5 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000255298 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059595 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8G5 olfactory receptor, family 8, subfamily G, member 5".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8G5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.