OR5H6

OR5H6
Identifiers
Aliases	OR5H6 , OR3-11, olfactory receptor family 5 subfamily H member 6 (gene/pseudogene), olfactory receptor family 5 subfamily H member 6
External IDs	MGI: 3030021 HomoloGene: 133069 GeneCards: OR5H6
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q11.2 Start 98,263,252 bp [1] End 98,265,356 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16|16 C1.3 Start 58,855,926 bp [2] End 58,860,130 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding signal transducer activity olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79295 258319 Ensembl ENSG00000230301 ENSMUSG00000043357 UniProt Q8NGV6 Q8VEX6 RefSeq (mRNA) NM_001005479 NM_146322 RefSeq (protein) NP_001005479 NP_666434 Location (UCSC) Chr 3: 98.26 – 98.27 Mb Chr 16: 58.86 – 58.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5H6 is a protein that in humans is encoded by the OR5H6 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000230301 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000043357 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5H6 olfactory receptor, family 5, subfamily H, member 6".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5H6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.