OR10A7

OR10A7
Identifiers
Aliases	OR10A7 , OR12-6, olfactory receptor family 10 subfamily A member 7
External IDs	HomoloGene: 78831 GeneCards: OR10A7
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.2 Start 55,221,025 bp [1] End 55,221,975 bp [1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	121364	n/a
Ensembl	ENSG00000179919	n/a
UniProt	Q8NGE5	n/a
RefSeq (mRNA)	NM_001005280	n/a
RefSeq (protein)	NP_001005280	n/a
Location (UCSC)	Chr 12: 55.22 – 55.22 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptor 10A7 is a protein that in humans is encoded by the OR10A7 gene. ^[3]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000179919 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR10A7 olfactory receptor, family 10, subfamily A, member 7".

Further reading

• Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR10A7+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.