OR2T6

OR2T6
Identifiers
Aliases	OR2T6 , OR2T6P, OR2T9, OST703, olfactory receptor family 2 subfamily T member 6
External IDs	MGI: 3030554 HomoloGene: 74036 GeneCards: OR2T6
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 248,375,746 bp [1] End 248,391,811 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 A1 Start 8,282,925 bp [2] End 8,298,025 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in kidney Top expressed in respiratory epithelium olfactory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 254879 258387 Ensembl ENSG00000198104 ENSG00000278689 ENSG00000278659 ENSMUSG00000052417 UniProt Q8NHC8 Q8VF37 RefSeq (mRNA) NM_001005471 NM_146392 RefSeq (protein) NP_001005471 NP_666504 Location (UCSC) Chr 1: 248.38 – 248.39 Mb Chr 14: 8.28 – 8.3 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2T6 is a protein that in humans is encoded by the OR2T6 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000278689, ENSG00000278659 GRCh38: Ensembl release 89: ENSG00000198104, ENSG00000278689, ENSG00000278659 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000052417 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2T6 olfactory receptor, family 2, subfamily T, member 6".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.

External links

• OR2T6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.