OR5AC2

OR5AC2
Identifiers
Aliases	OR5AC2 , HSA1, olfactory receptor family 5 subfamily AC member 2
External IDs	MGI: 3030032 HomoloGene: 51800 GeneCards: OR5AC2
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q11.2 Start 98,087,173 bp [1] End 98,088,102 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16|16 C1.3 Start 59,020,715 bp [2] End 59,023,896 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in temporal lobe testicle thoracic aorta brain ascending aorta multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81050 258036 Ensembl ENSG00000196578 ENSMUSG00000052537 UniProt Q9NZP5 Q7TS40 RefSeq (mRNA) NM_054106 NM_001011808 RefSeq (protein) NP_473447 NP_001011808 Location (UCSC) Chr 3: 98.09 – 98.09 Mb Chr 16: 59.02 – 59.02 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 5AC2 is a protein that in humans is encoded by the OR5AC2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196578 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000052537 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5AC2 olfactory receptor, family 5, subfamily AC, member 2".

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi: 10.1073/pnas.040580197 . PMC   16022 . PMID   10706615.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode:2006Natur.440.1194M. doi: 10.1038/nature04728 . PMID   16641997.

External links

• OR5AC2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.