OR52W1

OR52W1
Identifiers
Aliases	OR52W1 , OR11-71, OR52W1P, olfactory receptor family 52 subfamily W member 1
External IDs	MGI: 3030526 HomoloGene: 64859 GeneCards: OR52W1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 6,199,224 bp [1] End 6,200,186 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 105,017,437 bp [2] End 105,018,562 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex duodenum rectum Top expressed in hypothalamus superior frontal gyrus cerebellar cortex hippocampus proper oocyte olfactory bulb secondary oocyte mesencephalon More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 120787 258352 Ensembl ENSG00000175485 ENSMUSG00000073906 UniProt Q6IF63 Q8VF03 RefSeq (mRNA) NM_001005178 NM_146355 RefSeq (protein) NP_001005178 NP_666467 Location (UCSC) Chr 11: 6.2 – 6.2 Mb Chr 7: 105.02 – 105.02 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52W1 is a protein that in humans is encoded by the OR52W1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000175485 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000073906 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR52W1 olfactory receptor, family 52, subfamily W, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi: 10.1038/nature04632 . PMID   16554811.

External links

• OR52W1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.