OR2A14

OR2A14
Identifiers
Aliases	OR2A14 , OR2A14P, OR2A6, OST182, olfactory receptor family 2 subfamily A member 14
External IDs	MGI: 3030278 HomoloGene: 88438 GeneCards: OR2A14
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q35 Start 144,123,176 bp [1] End 144,131,188 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 B2.1 Start 42,926,001 bp [2] End 42,933,698 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in canal of the cervix gonad male reproductive system testicle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 135941 258650 Ensembl ENSG00000221938 ENSG00000284891 ENSMUSG00000073110 UniProt Q96R47 Q8VFS6 RefSeq (mRNA) NM_001001659 NM_146656 RefSeq (protein) NP_001001659 NP_666867 Location (UCSC) Chr 7: 144.12 – 144.13 Mb Chr 6: 42.93 – 42.93 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2A14 is a protein that in humans is encoded by the OR2A14 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000284891 GRCh38: Ensembl release 89: ENSG00000221938, ENSG00000284891 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000073110 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2A14 olfactory receptor, family 2, subfamily A, member 14".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2A14+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.