OR6K2

OR6K2
Identifiers
Aliases	OR6K2 , OR1-17, olfactory receptor family 6 subfamily K member 2
External IDs	MGI: 3030254 HomoloGene: 17185 GeneCards: OR6K2
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 158,699,678 bp [1] End 158,700,652 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H3 Start 173,983,199 bp [2] End 173,989,761 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Top expressed in bone marrow abdomen liver More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81448 258302 Ensembl ENSG00000196171 ENSMUSG00000055033 UniProt Q8NGY2 n/a RefSeq (mRNA) NM_001005279 NM_146305 RefSeq (protein) NP_001005279 n/a Location (UCSC) Chr 1: 158.7 – 158.7 Mb Chr 1: 173.98 – 173.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 6K2 is a protein that in humans is encoded by the OR6K2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196171 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000055033 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6K2 olfactory receptor, family 6, subfamily K, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6K2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.