OR2B2

OR2B2
Identifiers
Aliases	OR2B2 , OR2B2Q, OR2B9, OR6-1, dJ193B12.4, hs6M1-10, olfactory receptor family 2 subfamily B member 2
External IDs	MGI: 3031194 HomoloGene: 11056 GeneCards: OR2B2
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p22.1 Start 27,911,185 bp [1] End 27,912,396 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 A3.1 Start 21,857,601 bp [2] End 21,861,575 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibialis anterior muscle deltoid muscle lower lobe of lung monocyte Top expressed in testicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81697 258536 Ensembl ENSG00000168131 ENSMUSG00000108534 UniProt Q9GZK3 n/a RefSeq (mRNA) NM_033057 NM_146543 RefSeq (protein) NP_149046 n/a Location (UCSC) Chr 6: 27.91 – 27.91 Mb Chr 13: 21.86 – 21.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2B2 is a protein that in humans is encoded by the OR2B2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000168131 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000108534 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2B2 olfactory receptor, family 2, subfamily B, member 2".

Further reading

• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2B2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.