OR6V1

OR6V1
Identifiers
Aliases	OR6V1 , GPR138, olfactory receptor family 6 subfamily V member 1
External IDs	HomoloGene: 84582 GeneCards: OR6V1
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q34 Start 143,052,341 bp [1] End 143,053,282 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum sural nerve reproductive system reproductive organ gonad male reproductive system testicle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 346517 n/a Ensembl ENSG00000277378 ENSG00000225781 n/a UniProt Q8N148 n/a RefSeq (mRNA) NM_001001667 n/a RefSeq (protein) NP_001001667 n/a Location (UCSC) Chr 7: 143.05 – 143.05 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 6V1 is a protein that in humans is encoded by the OR6V1 gene. ^{[3] [4]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. ENSG00000225781 GRCh38: Ensembl release 89: ENSG00000277378, ENSG00000225781 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Vanti WB, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF (May 2003). "Novel human G-protein-coupled receptors". Biochem Biophys Res Commun. 305 (1): 67–71. doi:10.1016/S0006-291X(03)00709-5. PMID   12732197.
4. "Entrez Gene: OR6V1 olfactory receptor, family 6, subfamily V, member 1".

Further reading

• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC   2882961 . PMID   12690205.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6V1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.