OR5C1

OR5C1
Identifiers
Aliases	OR5C1 , OR5C2P, OR9-31, OR9-F, olfactory receptor family 5 subfamily C member 1
External IDs	MGI: 3030202 HomoloGene: 71970 GeneCards: OR5C1
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,788,933 bp [1] End 122,789,895 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 37,216,527 bp [2] End 37,222,784 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Top expressed in respiratory epithelium peripheral nervous system olfactory epithelium embryo More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 392391 258371 Ensembl ENSG00000148215 ENSMUSG00000049018 UniProt Q8NGR4 Q8VF22 RefSeq (mRNA) NM_001001923 NM_146374 RefSeq (protein) NP_001001923 NP_666486 Location (UCSC) Chr 9: 122.79 – 122.79 Mb Chr 2: 37.22 – 37.22 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5C1 is a protein that in humans is encoded by the OR5C1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000148215 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049018 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5C1 olfactory receptor, family 5, subfamily C, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5C1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.