OR10AG1

OR10AG1
Identifiers
Aliases	OR10AG1 , OR11-160, olfactory receptor family 10 subfamily AG member 1
External IDs	MGI: 3030957 HomoloGene: 105187 GeneCards: OR10AG1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 55,965,755 bp [1] End 55,969,945 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 87,246,979 bp [2] End 87,253,555 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 282770 258347 Ensembl ENSG00000174970 ENSMUSG00000043274 UniProt Q8NH19 A2AT85 RefSeq (mRNA) NM_001005491 NM_146350 RefSeq (protein) NP_001005491 NP_666462 Location (UCSC) Chr 11: 55.97 – 55.97 Mb Chr 2: 87.25 – 87.25 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10AG1 is a protein that in humans is encoded by the OR10AG1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000174970 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000043274 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10AG1 olfactory receptor, family 10, subfamily AG, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10AG1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.