OR5BF1

OR14C36
Identifiers
Aliases	OR14C36 , OR5BF1, olfactory receptor family 14 subfamily C member 36
External IDs	MGI: 3030135 HomoloGene: 128067 GeneCards: OR14C36
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 248,348,775 bp [1] End 248,349,713 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 D3 Start 86,053,054 bp [2] End 86,063,232 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hypothalamus tibial nerve prostate n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 127066 257958 Ensembl ENSG00000177174 ENSMUSG00000061549 UniProt Q8NHC7 Q7TS04 RefSeq (mRNA) NM_001001918 NM_212436 RefSeq (protein) NP_001001918 NP_997601 Location (UCSC) Chr 1: 248.35 – 248.35 Mb Chr 7: 86.05 – 86.06 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 14C36 is a protein that in humans is encoded by the OR14C36 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000177174 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000061549 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5BF1 olfactory receptor, family 5, subfamily BF, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.

External links

• OR5BF1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.