OR4K5

OR4K5
Identifiers
Aliases	OR4K5 , OR14-16, olfactory receptor family 4 subfamily K member 5
External IDs	MGI: 3030563 HomoloGene: 17167 GeneCards: OR4K5
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 19,920,582 bp [1] End 19,921,659 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 C1 Start 50,144,731 bp [2] End 50,152,910 bp [2]
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79317	258275
Ensembl	ENSG00000176281	ENSMUSG00000049011
UniProt	Q8NGD3	Q8VET4
RefSeq (mRNA)	NM_001005483	NM_146278
RefSeq (protein)	NP_001005483	NP_666390
Location (UCSC)	Chr 14: 19.92 – 19.92 Mb	Chr 14: 50.14 – 50.15 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4K5 is a protein that in humans is encoded by the OR4K5 gene. ^{[5] [6]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[6]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000176281 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049011 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.
6. "Entrez Gene: OR4K5 olfactory receptor, family 4, subfamily K, member 5".

External links

• OR4K5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.