OR8H2

OR8H2
Identifiers
Aliases	OR8H2 , OR11-171, olfactory receptor family 8 subfamily H member 2
External IDs	MGI: 3030934 HomoloGene: 34954 GeneCards: OR8H2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,103,687 bp [1] End 56,107,658 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,806,373 bp [2] End 86,810,298 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in adipose tissue blood multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390151 258587 Ensembl ENSG00000181767 ENSMUSG00000070875 UniProt Q8N162 Q8VFM1 RefSeq (mRNA) NM_001005200 NM_001386064 NM_146594 RefSeq (protein) NP_001005200 NP_666805 Location (UCSC) Chr 11: 56.1 – 56.11 Mb Chr 2: 86.81 – 86.81 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8H2 is a protein that in humans is encoded by the OR8H2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181767 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000070875 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8H2 olfactory receptor, family 8, subfamily H, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8H2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.