OR2L8

OR2L8
Identifiers
Aliases	OR2L8 , olfactory receptor family 2 subfamily L member 8 (gene/pseudogene), olfactory receptor family 2 subfamily L member 8
External IDs	HomoloGene: 128185 GeneCards: OR2L8
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 247,948,858 bp [1] End 247,949,796 bp [1]
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity molecular function Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 391190 n/a Ensembl ENSG00000279263 n/a UniProt Q8NGY9 n/a RefSeq (mRNA) NM_001001963 n/a RefSeq (protein) NP_001001963 n/a Location (UCSC) Chr 1: 247.95 – 247.95 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 2L8 is a protein that in humans is encoded by the OR2L8 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000279263 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR2L8 olfactory receptor, family 2, subfamily L, member 8".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2L8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.