OR6B2

OR6B2
Identifiers
Aliases	OR6B2 , OR2-1, OR6B2P, olfactory receptor family 6 subfamily B member 2
External IDs	MGI: 3031250 HomoloGene: 17472 GeneCards: OR6B2
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q37.3 Start 240,029,491 bp [1] End 240,030,429 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 D Start 92,403,647 bp [2] End 92,412,835 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve left coronary artery exocrine gland head salivary gland fundus integument integument minor salivary gland subcutaneous adipose tissue n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 389090 259040 Ensembl ENSG00000182083 ENSMUSG00000067064 UniProt Q6IFH4 Q8VGU4 RefSeq (mRNA) NM_001005853 NM_001001962 NM_147038 RefSeq (protein) NP_001005853 NP_667249 Location (UCSC) Chr 2: 240.03 – 240.03 Mb Chr 1: 92.4 – 92.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 6B2 is a protein that in humans is encoded by the OR6B2 gene. ^[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000182083 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067064 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6B2 olfactory receptor, family 6, subfamily B, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6B2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.