OR4C16

OR4C16
Identifiers
Aliases	OR4C16 , OR11-135, olfactory receptor family 4 subfamily C member 16 (gene/pseudogene), olfactory receptor family 4 subfamily C member 16
External IDs	MGI: 3031043 HomoloGene: 128155 GeneCards: OR4C16
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q11 Start 55,572,128 bp [1] End 55,573,060 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E1 Start 88,735,286 bp [2] End 88,745,501 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219428 258453 Ensembl ENSG00000279514 ENSMUSG00000075113 UniProt Q8NGL9 Q3SXJ3 RefSeq (mRNA) NM_001004701 NM_146461 RefSeq (protein) NP_001004701 NP_666672 Location (UCSC) Chr 11: 55.57 – 55.57 Mb Chr 2: 88.74 – 88.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4C16 is a protein that in humans is encoded by the OR4C16 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000279514 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075113 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4C16 olfactory receptor, family 4, subfamily C, member 16".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi: 10.1038/nature04632 . PMID   16554811.

External links

• OR4C16+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.