OR6T1

OR6T1
Identifiers
Aliases	OR6T1 , OR11-277, olfactory receptor family 6 subfamily T member 1
External IDs	GeneCards: OR6T1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.1 Start 123,942,867 bp [1] End 123,943,838 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas rectum islet of Langerhans n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity neurotransmitter receptor activity G protein-coupled serotonin receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane dendrite Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219874 n/a Ensembl ENSG00000181499 n/a UniProt Q8NGN1 n/a RefSeq (mRNA) NM_001005187 n/a RefSeq (protein) NP_001005187 n/a Location (UCSC) Chr 11: 123.94 – 123.94 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 6T1 is a protein that in humans is encoded by the OR6T1 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181499 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR6T1 olfactory receptor, family 6, subfamily T, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6T1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.