OR2A2

OR2A2
Identifiers
Aliases	OR2A2 , OR2A17P, OR2A2P, OR7-11, OST008, olfactory receptor family 2 subfamily A member 2
External IDs	HomoloGene: 133887 GeneCards: OR2A2
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q35 Start 144,109,583 bp [1] End 144,110,539 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence renal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 442361 n/a Ensembl ENSG00000221989 ENSG00000285071 n/a UniProt Q6IF42 n/a RefSeq (mRNA) NM_001005480 n/a RefSeq (protein) NP_001005480 n/a Location (UCSC) Chr 7: 144.11 – 144.11 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 2A2 is a protein that in humans is encoded by the OR2A2 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. ENSG00000285071 GRCh38: Ensembl release 89: ENSG00000221989, ENSG00000285071 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR2A2 olfactory receptor, family 2, subfamily A, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2A2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.