OR1D5

OR1D5
Identifiers
Aliases	OR1D5 , C17orf2, OR17-2, OR17-30, OR17-31, OR1D4, olfactory receptor family 1 subfamily D member 5
External IDs	HomoloGene: 105312 GeneCards: OR1D5
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17p13.3 Start 3,062,669 bp [1] End 3,063,607 bp [1]
Gene ontology Molecular function • signal transducer activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway • detection of chemical stimulus involved in sensory perception of smell Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8386	n/a
Ensembl	ENSG00000262628	n/a
UniProt	P58170	n/a
RefSeq (mRNA)	NM_014566	n/a
RefSeq (protein)	NP_055381	n/a
Location (UCSC)	Chr 17: 3.06 – 3.06 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene. ^{[3] [4]} Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

References

1. GRCh38: Ensembl release 89: ENSG00000262628 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID   10673334.
4. "Entrez Gene: OR1D5 olfactory receptor, family 1, subfamily D, member 5".

Further reading

• Selbie LA, Townsend-Nicholson A, Iismaa TP, Shine J (1992). "Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences". Brain Res. Mol. Brain Res. 13 (1–2): 159–63. doi:10.1016/0169-328X(92)90057-I. PMID   1315913.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC   139241 . PMID   12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR1D5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.