OR10AD1

OR10AD1
Identifiers
Aliases	OR10AD1 , OR10AD1P, OR12-1, olfactory receptor family 10 subfamily AD member 1
External IDs	MGI: 3030122 HomoloGene: 128379 GeneCards: OR10AD1
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.11 Start 48,202,083 bp [1] End 48,203,387 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 F1 Start 98,186,013 bp [2] End 98,195,542 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	121275	545140
Ensembl	ENSG00000172640	ENSMUSG00000075427
UniProt	Q8NGE0	E9Q1P2
RefSeq (mRNA)	NM_001004134	NM_001011733
RefSeq (protein)	NP_001004134	NP_001011733
Location (UCSC)	Chr 12: 48.2 – 48.2 Mb	Chr 15: 98.19 – 98.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10AD1 is a protein that in humans is encoded by the OR10AD1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172640 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075427 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10AD1 olfactory receptor, family 10, subfamily AD, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR10AD1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.