OR5AR1

OR5AR1
Identifiers
Aliases	OR5AR1 , OR11-209, olfactory receptor family 5 subfamily AR member 1 (gene/pseudogene), olfactory receptor family 5 subfamily AR member 1
External IDs	MGI: 3030853 HomoloGene: 17464 GeneCards: OR5AR1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,663,686 bp [1] End 56,664,618 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 85,669,965 bp [2] End 85,675,827 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity odorant binding copper ion binding Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway detection of chemical stimulus involved in sensory perception Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219493 259017 Ensembl ENSG00000172459 ENSMUSG00000075208 UniProt Q8NGP9 Q8VGS3 RefSeq (mRNA) NM_001004730 NM_147015 RefSeq (protein) NP_001004730 NP_667226 Location (UCSC) Chr 11: 56.66 – 56.66 Mb Chr 2: 85.67 – 85.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5AR1 is a protein that in humans is encoded by the OR5AR1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172459 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075208 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5AR1 olfactory receptor, family 5, subfamily AR, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5AR1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.