OR1S1

OR1S1
Identifiers
Aliases	OR1S1 , OR11-232, OST034, olfactory receptor family 1 subfamily S member 1 (gene/pseudogene), olfactory receptor family 1 subfamily S member 1
External IDs	MGI: 3031330 HomoloGene: 17458 GeneCards: OR1S1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 58,212,720 bp [1] End 58,216,084 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 13,755,242 bp [2] End 13,760,284 bp [2]
Gene ontology Molecular function transmembrane signaling receptor activity G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception of smell sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219959 258991 Ensembl ENSG00000280204 ENSMUSG00000048356 UniProt Q8NH92 B9EHG2 RefSeq (mRNA) NM_001004458 NM_146989 RefSeq (protein) NP_001004458 NP_667200 Location (UCSC) Chr 11: 58.21 – 58.22 Mb Chr 19: 13.76 – 13.76 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 1S1 is a protein that in humans is encoded by the OR1S1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000280204 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048356 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1S1 olfactory receptor, family 1, subfamily S, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR1S1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.