OR56B4

OR56B4
Identifiers
Aliases	OR56B4 , OR11-67, olfactory receptor family 56 subfamily B member 4
External IDs	MGI: 3030497 HomoloGene: 133594 GeneCards: OR56B4
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 6,107,684 bp [1] End 6,108,835 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 104,352,776 bp [2] End 104,353,734 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in smooth muscle tissue monocyte rectum appendix islet of Langerhans duodenum right coronary artery salivary gland reproductive system reproductive organ n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 196335 257914 Ensembl ENSG00000180919 ENSMUSG00000109806 UniProt Q8NH76 Q7TRP6 RefSeq (mRNA) NM_001005181 NM_001011757 RefSeq (protein) NP_001005181 NP_001011757 Location (UCSC) Chr 11: 6.11 – 6.11 Mb Chr 7: 104.35 – 104.35 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 56B4 is a protein that in humans is encoded by the OR56B4 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000180919 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000109806 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR56B4 olfactory receptor, family 56, subfamily B, member 4".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR56B4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.