OR6B1

OR6B1
Identifiers
Aliases	OR6B1 , OR7-3, OR7-9, olfactory receptor family 6 subfamily B member 1
External IDs	MGI: 3030283 HomoloGene: 17485 GeneCards: OR6B1
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q35 Start 144,000,320 bp [1] End 144,008,793 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 B2.1 Start 42,811,318 bp [2] End 42,816,450 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta thymus testicle stomach n/a More reference expression data BioGPS n/a
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 135946 259067 Ensembl ENSG00000221813 ENSG00000284939 ENSMUSG00000049168 UniProt O95007 n/a RefSeq (mRNA) NM_001005281 NM_001356410 RefSeq (protein) NP_001005281 n/a Location (UCSC) Chr 7: 144 – 144.01 Mb Chr 6: 42.81 – 42.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 6B1 is a protein that in humans is encoded by the OR6B1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000284939 GRCh38: Ensembl release 89: ENSG00000221813, ENSG00000284939 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049168 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6B1 olfactory receptor, family 6, subfamily B, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6B1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.