OR3A4

OR3A4P
Identifiers
Aliases	OR3A4P , OLFRA05, OLFRA06, OR17-13, OR17-16, OR17-24, OR17-25, OR24, OR25, OR3A4, OR3A5P, olfactory receptor family 3 subfamily A member 4 pseudogene
External IDs	GeneCards: OR3A4P
Orthologs
Species	Human	Mouse
Entrez	390756	n/a
Ensembl	ENSG00000180068	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	NM_001005334	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wikidata
View/Edit Human

Olfactory receptor 3A4 is a protein that in humans is encoded by the OR3A4 gene. ^[2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[2]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
2. "Entrez Gene: OR3A4 olfactory receptor, family 3, subfamily A, member 4".

Further reading

• Ben-Arie N, Lancet D, Taylor C, et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum. Mol. Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID   8004088.
• Glusman G, Clifton S, Roe B, Lancet D (1997). "Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity". Genomics. 37 (2): 147–60. doi:10.1006/geno.1996.0536. PMID   8921386.
• Glusman G, Sosinsky A, Ben-Asher E, et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID   10673334. S2CID   23416814.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR3A4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.