OR5M1

OR5M1
Identifiers
Aliases	OR5M1 , OR11-208, OST050, olfactory receptor family 5 subfamily M member 1
External IDs	MGI: 3030857 HomoloGene: 128087 GeneCards: OR5M1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,609,236 bp [1] End 56,614,874 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 85,715,984 bp [2] End 85,721,557 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreas islet of Langerhans multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390168 258580 Ensembl ENSG00000255012 ENSMUSG00000050128 UniProt Q8NGP8 A2ASU6 RefSeq (mRNA) NM_001004740 NM_146587 RefSeq (protein) NP_001004740 NP_666798 Location (UCSC) Chr 11: 56.61 – 56.61 Mb Chr 2: 85.72 – 85.72 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5M1 is a protein that in humans is encoded by the OR5M1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000255012 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050128 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5M1 olfactory receptor, family 5, subfamily M, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5M1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.