OR4C15

OR4C15
Identifiers
Aliases	OR4C15 , OR11-127, OR11-134, olfactory receptor family 4 subfamily C member 15
External IDs	MGI: 3031045 HomoloGene: 81548 GeneCards: OR4C15
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q11 Start 55,554,307 bp [1] End 55,555,419 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E1 Start 88,757,220 bp [2] End 88,768,455 bp [2]
Gene ontology Molecular function transmembrane signaling receptor activity signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of smell signal transduction detection of chemical stimulus involved in sensory perception of smell response to stimulus detection of chemical stimulus involved in sensory perception G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81309 258025 Ensembl ENSG00000181939 ENSMUSG00000075112 UniProt Q8NGM1 Q7TR09 RefSeq (mRNA) NM_001001920 NM_001011804 RefSeq (protein) NP_001001920 NP_001011804 Location (UCSC) Chr 11: 55.55 – 55.56 Mb Chr 2: 88.76 – 88.77 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 4C15 is a protein that in humans is encoded by the OR4C15 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181939 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075112 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4C15 olfactory receptor, family 4, subfamily C, member 15".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4C15+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.