Salbutamol/budesonide

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Salbutamol/budesonide
Combination of
Salbutamol Beta2-adrenergic agonist
Budesonide Corticosteroid
Clinical data
Trade names Airsupra
Other namesPT027, albuterol/budesonide
AHFS/Drugs.com Monograph
License data
Routes of
administration 		Inhalation
ATC code
Legal status
Legal status
Identifiers
KEGG

Salbutamol/budesonide, sold under the brand name Airsupra, is a fixed-dose combination medication for the treatment of bronchoconstriction and asthma. [1] [2] It is a combination of salbutamol sulfate (albuterol sulfate), a short-acting beta2-adrenergic agonist, and budesonide, an inhaled corticosteroid. [1] [2] It is inhaled using a pressurized metered-dose inhaler. [1] [2]

Contents

The most common side effects include headache, oral candidiasis, cough, and difficulty speaking. [2]

Salbutamol/budesonide was approved for medical use in the United States in January 2023. [2] [3] It is the first combination of an inhaled corticosteroid and a short-acting beta-agonist to be approved by the US Food and Drug Administration (FDA). [2] It is the first product containing an inhaled corticosteroid to be approved by the FDA as a reliever treatment (rather than as a controller) for asthma. [2]

Medical uses

Salbutamol/budesonide is indicated for the as-needed treatment or prevention of bronchoconstriction and to reduce the risk of asthma attacks. [1] [2]

History

The efficacy of salbutamol/budesonide to reduce the risk of severe asthma attacks was evaluated in participants with moderate to severe asthma in MANDALA (NCT03769090), a randomized, double-blind, multicenter study. [2]

References

  1. 1 2 3 4 5 "Airsupra- albuterol sulfate and budesonide aerosol, metered". DailyMed. 7 March 2024. Retrieved 16 May 2024.
  2. 1 2 3 4 5 6 7 8 9 "FDA approves drug combination treatment for adults with asthma". U.S. Food and Drug Administration. 11 January 2023. Archived from the original on 20 January 2023. Retrieved 20 January 2023.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  3. ↑ "Airsupra (PT027) approved in the US for asthma". AstraZeneca (Press release). 11 January 2023. Archived from the original on 20 January 2023. Retrieved 20 January 2023.

Further reading

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