CAMK1

Last updated
CAMK1
Protein CAMK1 PDB 1a06.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CAMK1 , CAMKI, calcium/calmodulin dependent protein kinase I, CaMKI-alpha, CaM kinase I alpha
External IDs OMIM: 604998 MGI: 1098535 HomoloGene: 117458 GeneCards: CAMK1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003656

NM_133926

RefSeq (protein)

NP_003647
NP_003647.1

NP_598687

Location (UCSC) Chr 3: 9.76 – 9.77 Mb Chr 6: 113.31 – 113.32 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Calcium/calmodulin-dependent protein kinase type 1 is an enzyme that in humans is encoded by the CAMK1 gene. [5] [6]

Contents

Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [6]

Related Research Articles

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<span class="mw-page-title-main">CAMK2G</span> Protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene.

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<span class="mw-page-title-main">CAMKK1</span> Protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene.

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<span class="mw-page-title-main">Synapsin I</span> Protein-coding gene in the species Homo sapiens

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000134072 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030272 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Haribabu B, Hook SS, Selbert MA, Goldstein EG, Tomhave ED, Edelman AM, Snyderman R, Means AR (Sep 1995). "Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase". EMBO J. 14 (15): 3679–86. doi:10.1002/j.1460-2075.1995.tb00037.x. PMC   394442 . PMID   7641687.
  6. 1 2 "Entrez Gene: CAMK1 calcium/calmodulin-dependent protein kinase I".

Further reading