TSSK2

TSSK2
Identifiers
Aliases	TSSK2 , DGS-G, SPOGA2, STK22B, TSK2, testis specific serine kinase 2
External IDs	OMIM: 610710; MGI: 1347559; HomoloGene: 31512; GeneCards: TSSK2; OMA:TSSK2 - orthologs
Gene location (Human) Chr. Chromosome 22 (human) [1] Band 22q11.21 Start 19,131,308 bp [1] End 19,132,622 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16 A3|16 11.09 cM Start 17,716,501 bp [2] End 17,717,888 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis testicle sperm gonad tibialis anterior muscle ganglionic eminence tail of epididymis deltoid muscle ventricular zone Top expressed in spermatid testicle spermatocyte liver embryo secondary oocyte islet of Langerhans skeletal muscle tissue urinary bladder bone marrow More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity metal ion binding kinase activity protein serine/threonine kinase activity protein binding ATP binding magnesium ion binding protein-containing complex binding Cellular component cytoplasm acrosomal vesicle centriole cytoskeleton nucleus Biological process cell differentiation intracellular signal transduction phosphorylation multicellular organism development protein phosphorylation spermatogenesis spermatid development protein autophosphorylation peptidyl-serine phosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23617 22115 Ensembl ENSG00000206203 ENSMUSG00000045521 UniProt Q96PF2 O54863 RefSeq (mRNA) NM_053006 NM_009436 RefSeq (protein) NP_443732 NP_033462 Location (UCSC) Chr 22: 19.13 – 19.13 Mb Chr 16: 17.72 – 17.72 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Testis-specific serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the TSSK2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000206203 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000045521 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–495. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID   10591208.
6. "Entrez Gene: TSSK2 testis-specific serine kinase 2".

Further reading

• Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10) R84. doi: 10.1186/gb-2004-5-10-r84 . PMC   545604 . PMID   15461802.
• Hao Z, Jha KN, Kim YH, Vemuganti S, Westbrook VA, Chertihin O, Markgraf K, Flickinger CJ, Coppola M, Herr JC, Visconti PE (2005). "Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm". Mol. Hum. Reprod. 10 (6): 433–444. doi: 10.1093/molehr/gah052 . PMID   15044604.
• Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S, Bono H, Okazaki Y, Hayashizaki Y (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–1765. doi:10.1101/gr.180101. PMC   311163 . PMID   11591653.
• Kueng P, Nikolova Z, Djonov V, Hemphill A, Rohrbach V, Boehlen D, Zuercher G, Andres AC, Ziemiecki A (1998). "A novel family of serine/threonine kinases participating in spermiogenesis". J. Cell Biol. 139 (7): 1851–1859. doi:10.1083/jcb.139.7.1851. PMC   2132653 . PMID   9412477.
• Gong W, Emanuel BS, Collins J, Kim DH, Wang Z, Chen F, Zhang G, Roe B, Budarf ML (1996). "A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11". Hum. Mol. Genet. 5 (6): 789–800. CiteSeerX   10.1.1.539.9441 . doi:10.1093/hmg/5.6.789. PMID   8776594.