STK40

STK40
Identifiers
Aliases	STK40 , SHIK, SgK495, serine/threonine kinase 40
External IDs	OMIM: 609437 MGI: 1921428 HomoloGene: 12542 GeneCards: STK40
Gene location (Human)
Chr.	Chromosome 1 (human)
End	36,385,924 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	126,034,822 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; blood; ; monocyte; ; right coronary artery; ; islet of Langerhans; ; popliteal artery; ; amniotic fluid; ; ascending aorta; ; left ventricle; ; left coronary artery;
	Top expressed in
	plantaris muscle; ; skeletal muscle tissue; ; knee joint; ; extensor digitorum longus muscle; ; entorhinal cortex; ; right ventricle; ; lip; ; internal carotid artery; ; gastrocnemius muscle; ; tibialis anterior muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity ; nucleotide binding ; protein kinase activity ; protein serine/threonine kinase activity ; protein binding ; ATP binding ; kinase activity ;
Cellular component	nucleus ; nucleoplasm ; cytoplasm ; cytosol ;
Biological process	glycogen metabolic process ; regulation of gene expression ; protein phosphorylation ; lung alveolus development ; respiratory system process ; negative regulation of apoptotic process ; regulation of MAPK cascade ; lung morphogenesis ; phosphorylation ; multicellular organism growth ; lung development ;
	Sources:Amigo / QuickGO
Orthologs
	83931
	74178
	ENSG00000196182
	ENSMUSG00000042608
	Q8N2I9
	Q7TNL3
	NM_032017 ; NM_001282546 ; NM_001282547
	NM_001145827 ; NM_028800
	NP_001269475 ; NP_001269476 ; NP_114406
	NP_001139299 ; NP_083076
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 12, 2022

Serine/threonine-protein kinase 40 is an enzyme that in humans is encoded by the STK40 gene.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000196182 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042608 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: STK40 serine/threonine kinase 40".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Huang J, Teng L, Liu T, et al. (2003). "Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced transcription". Biochem. Biophys. Res. Commun. 309 (4): 774–8. doi:10.1016/j.bbrc.2003.08.069. PMID 13679039.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID 16710414.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000196182 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042608 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: STK40 serine/threonine kinase 40".

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v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

STK40

Related Research Articles

References

Further reading