STK40

STK40
Identifiers
Aliases	STK40 , SHIK, SgK495, serine/threonine kinase 40
External IDs	OMIM: 609437; MGI: 1921428; HomoloGene: 12542; GeneCards: STK40; OMA:STK40 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p34.3 Start 36,339,624 bp [1] End 36,385,924 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 D2.2 Start 125,997,750 bp [2] End 126,034,822 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle blood muscle of thigh granulocyte left testis right testis monocyte apex of heart right coronary artery islet of Langerhans Top expressed in Ileal epithelium lactiferous gland muscle of thigh granulocyte plantaris muscle perirhinal cortex skeletal muscle tissue knee joint extensor digitorum longus muscle entorhinal cortex More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity Cellular component nucleus nucleoplasm cytoplasm cytosol Biological process glycogen metabolic process regulation of gene expression protein phosphorylation lung alveolus development respiratory system process negative regulation of apoptotic process regulation of MAPK cascade lung morphogenesis phosphorylation multicellular organism growth lung development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83931 74178 Ensembl ENSG00000196182 ENSMUSG00000042608 UniProt Q8N2I9 Q7TNL3 RefSeq (mRNA) NM_032017 NM_001282546 NM_001282547 NM_001145827 NM_028800 RefSeq (protein) NP_001269475 NP_001269476 NP_114406 NP_001139299 NP_083076 Location (UCSC) Chr 1: 36.34 – 36.39 Mb Chr 4: 126 – 126.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein kinase 40 is an enzyme that in humans is encoded by the STK40 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000196182 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042608 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: STK40 serine/threonine kinase 40".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Huang J, Teng L, Liu T, et al. (2003). "Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced transcription". Biochem. Biophys. Res. Commun. 309 (4): 774–8. doi:10.1016/j.bbrc.2003.08.069. PMID   13679039.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.