4F-PHP

4-Fluoro-alpha-PHP

Legal status
Legal status	US:Unscheduled, illegal in Virginia [1]
Identifiers
IUPAC name 1-(4-fluorophenyl)-2-(pyrrolidin-1-yl)hexan-1-one
CAS Number	2230706-09-7
PubChem CID	132989300
CompTox Dashboard (EPA)	DTXSID201341964
Chemical and physical data
Formula	C16H22FNO
Molar mass	263.356 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCC(C(=O)C1=CC=C(C=C1)F)N2CCCC2
InChI InChI=1S/C16H22FNO/c1-2-3-6-15(18-11-4-5-12-18)16(19)13-7-9-14(17)10-8-13/h7-10,15H,2-6,11-12H2,1H3 Key:BCJXLSGKMNRRKO-UHFFFAOYSA-N

4-Fluoro-alpha-PHP (4F-PHP) is a recreational designer drug from the substituted cathinone family with stimulant effects, which first appeared on the illicit market in around 2017. ^{[2] [3] [4]} This compound is structurally related to other well-known stimulants and has garnered attention for its potential to mimic the effects of traditional amphetamines, leading users to seek it out for its energizing and euphoric properties.

See also

• α-PHP
• 3F-PVP
• 3F-NEH
• 3F-PHP
• 3F-PiHP
• 4F-PVP
• 4Cl-PVP
• 4-Cl-PHP
• 4F-POP
• MFPVP
• MDPHP
• N-Ethylhexedrone
• N-Ethylhexylone

References

1. "§ 54.1-3446. Schedule I." Virginia Law. Retrieved 15 September 2023.
2. Liu C, Jia W, Li T, Hua Z, Qian Z (August 2017). "Identification and analytical characterization of nine synthetic cathinone derivatives N-ethylhexedrone, 4-Cl-pentedrone, 4-Cl-α-EAPP, propylone, N-ethylnorpentylone, 6-MeO-bk-MDMA, α-PiHP, 4-Cl-α-PHP, and 4-F-α-PHP". Drug Testing and Analysis. 9 (8): 1162–1171. doi:10.1002/dta.2136. PMID   27863142.
3. Apirakkan O, Frinculescu A, Shine T, Parkin MC, Cilibrizzi A, Frascione N, Abbate V (February 2018). "Analytical characterization of three cathinone derivatives, 4-MPD, 4F-PHP and bk-EPDP, purchased as bulk powder from online vendors". Drug Testing and Analysis. 10 (2): 372–378. doi:10.1002/dta.2218. PMID   28544816. S2CID   3542312.
4. Eshleman AJ, Nagarajan S, Wolfrum KM, Reed JF, Swanson TL, Nilsen A, Janowsky A (March 2019). "Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters". Psychopharmacology. 236 (3): 939–952. doi:10.1007/s00213-018-5059-5. PMC   6500773 . PMID   30397775.