Furostilbestrol

Last updated
Furostilbestrol
Furostilbestrol.svg
Identifiers
  • 4-[(3E)-4-[4-(furan-2-carbonyloxy)phenyl]hex-3-en-3-yl]phenyl furan-2-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.008.151 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C28H24O6
Molar mass 456.494 g·mol−1
3D model (JSmol)
  • CCC(=C(CC)C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C3=CC=C(C=C3)OC(=O)C4=CC=CO4
  • InChI=1S/C28H24O6/c1-3-23(19-9-13-21(14-10-19)33-27(29)25-7-5-17-31-25)24(4-2)20-11-15-22(16-12-20)34-28(30)26-8-6-18-32-26/h5-18H,3-4H2,1-2H3/b24-23+
  • Key:VUDMUAVGKIZQRY-WCWDXBQESA-N

Furostilbestrol (INN), also known as diethylstilbestrol di(2-furoate) [1] or simply as diethylstilbestrol difuroate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol, that was never marketed. [2] [3] It is an ester of diethylstilbestrol and was described in the literature in 1952. [2]

See also

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<span class="mw-page-title-main">Terfluranol</span> Synthetic estrogen

Terfluranol is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that was developed for the treatment of breast cancer but was never marketed. It was described in the medical literature in 1974.

<span class="mw-page-title-main">Pentafluranol</span> Chemical compound

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<span class="mw-page-title-main">Diethylstilbestrol diacetate</span> Chemical compound

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<span class="mw-page-title-main">Diethylstilbestrol monobenzyl ether</span> Chemical compound

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<span class="mw-page-title-main">Diethylstilbestrol disulfate</span> Chemical compound

Diethylstilbestrol disulfate is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was formerly marketed but is now no longer available. It is described as an antineoplastic agent.

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<span class="mw-page-title-main">Triphenylchloroethylene</span> Synthetic form of estrogen

Triphenylchloroethylene, or triphenylchlorethylene, also known as chlorotriphenylethylene or as phenylstilbene chloride, is a synthetic nonsteroidal estrogen of the triphenylethylene group that was marketed in the 1940s for the treatment of menopausal symptoms, vaginal atrophy, lactation suppression, and all other estrogen-indicated conditions.

References

  1. Marler EE (1976). Pharmacological and Chemical Synonyms: A Collection of Names of Drugs, Pesticides and Other Compounds Drawn from the Medical Literature of the World. Excerpta Medica. p. 150. ISBN   978-90-219-0298-2.
  2. 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 587. ISBN   978-1-4757-2085-3.
  3. World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 95, archived from the original (PDF) on August 8, 2016