This article may be too technical for most readers to understand.(April 2019) |
In statistical hypothesis testing, a type I error, or a false positive, is the rejection of the null hypothesis when it is actually true. A type II error, or a false negative, is the failure to reject a null hypothesis that is actually false. [1]
Type I error: an innocent person may be convicted. Type II error: a guilty person may be not convicted.
Much of statistical theory revolves around the minimization of one or both of these errors, though the complete elimination of either is an impossibility if the outcome is not determined by a known, observable causal process. The knowledge of type I errors and type II errors is widely used in medical science, biometrics and computer science.
Type I errors can be thought of as errors of commission (i.e., wrongly including a 'false case'). For instance, consider testing patients for a virus infection. If when the patient is not infected with the virus, but the test shows that they do, this is considered a type I error.
By contrast, type II errors are errors of omission (i.e, wrongly leaving out a 'true case'). In the example above, if the patient is infected by the virus, but the test shows that they are not, that would be a type II error.
In statistical test theory, the notion of a statistical error is an integral part of hypothesis testing. The test goes about choosing about two competing propositions called null hypothesis, denoted by and alternative hypothesis, denoted by . This is conceptually similar to the judgement in a court trial. The null hypothesis corresponds to the position of the defendant: just as he is presumed to be innocent until proven guilty, so is the null hypothesis presumed to be true until the data provide convincing evidence against it. The alternative hypothesis corresponds to the position against the defendant. Specifically, the null hypothesis also involves the absence of a difference or the absence of an association. Thus, the null hypothesis can never be that there is a difference or an association.
If the result of the test corresponds with reality, then a correct decision has been made. However, if the result of the test does not correspond with reality, then an error has occurred. There are two situations in which the decision is wrong. The null hypothesis may be true, whereas we reject . On the other hand, the alternative hypothesis may be true, whereas we do not reject . Two types of error are distinguished: type I error and type II error. [2]
The first kind of error is the mistaken rejection of a null hypothesis as the result of a test procedure. This kind of error is called a type I error (false positive) and is sometimes called an error of the first kind. In terms of the courtroom example, a type I error corresponds to convicting an innocent defendant.
The second kind of error is the mistaken failure to reject the null hypothesis as the result of a test procedure. This sort of error is called a type II error (false negative) and is also referred to as an error of the second kind. In terms of the courtroom example, a type II error corresponds to acquitting a criminal. [2]
The crossover error rate (CER) is the point at which type I errors and type II errors are equal. A system with a lower CER value provides more accuracy than a system with a higher CER value.
In terms of false positives and false negatives, a positive result corresponds to rejecting the null hypothesis, while a negative result corresponds to failing to reject the null hypothesis; "false" means the conclusion drawn is incorrect. Thus, a type I error is equivalent to a false positive, and a type II error is equivalent to a false negative.
Tabulated relations between truth/falseness of the null hypothesis and outcomes of the test: [3]
Table of error types | Null hypothesis () is | ||
---|---|---|---|
True | False | ||
Decision about null hypothesis () | Not reject | Correct inference (true negative) (probability = ) | Type II error (false negative) (probability = ) |
Reject | Type I error (false positive) (probability = ) | Correct inference (true positive) (probability = ) |
A perfect test would have zero false positives and zero false negatives. However, statistical methods are probabilistic, and it cannot be known for certain whether statistical conclusions are correct. Whenever there is uncertainty, there is the possibility of making an error. Considering this, all statistical hypothesis tests have a probability of making type I and type II errors. [4]
These two types of error rates are traded off against each other: for any given sample set, the effort to reduce one type of error generally results in increasing the other type of error.[ citation needed ]
The same idea can be expressed in terms of the rate of correct results and therefore used to minimize error rates and improve the quality of hypothesis test. To reduce the probability of committing a type I error, making the alpha value more stringent is both simple and efficient. To decrease the probability of committing a type II error, which is closely associated with analyses' power, either increasing the test's sample size or relaxing the alpha level could increase the analyses' power.[ citation needed ] A test statistic is robust if the type I error rate is controlled.
Varying different threshold (cut-off) values could also be used to make the test either more specific or more sensitive, which in turn elevates the test quality. For example, imagine a medical test, in which an experimenter might measure the concentration of a certain protein in the blood sample. The experimenter could adjust the threshold (black vertical line in the figure) and people would be diagnosed as having diseases if any number is detected above this certain threshold. According to the image, changing the threshold would result in changes in false positives and false negatives, corresponding to movement on the curve.[ citation needed ]
Since in a real experiment it is impossible to avoid all type I and type II errors, it is important to consider the amount of risk one is willing to take to falsely reject H0 or accept H0. The solution to this question would be to report the p-value or significance level α of the statistic. For example, if the p-value of a test statistic result is estimated at 0.0596, then there is a probability of 5.96% that we falsely reject H0. Or, if we say, the statistic is performed at level α, like 0.05, then we allow to falsely reject H0 at 5%. A significance level α of 0.05 is relatively common, but there is no general rule that fits all scenarios.
The speed limit of a freeway in the United States is 120 kilometers per hour (75 mph). A device is set to measure the speed of passing vehicles. Suppose that the device will conduct three measurements of the speed of a passing vehicle, recording as a random sample X1, X2, X3. The traffic police will or will not fine the drivers depending on the average speed . That is to say, the test statistic
In addition, we suppose that the measurements X1, X2, X3 are modeled as normal distribution N(μ,2). Then, T should follow N(μ,2/) and the parameter μ represents the true speed of passing vehicle. In this experiment, the null hypothesis H0 and the alternative hypothesis H1 should be
H0: μ=120 against H1: μ>120.
If we perform the statistic level at α=0.05, then a critical value c should be calculated to solve
According to change-of-units rule for the normal distribution. Referring to Z-table, we can get
Here, the critical region. That is to say, if the recorded speed of a vehicle is greater than critical value 121.9, the driver will be fined. However, there are still 5% of the drivers are falsely fined since the recorded average speed is greater than 121.9 but the true speed does not pass 120, which we say, a type I error.
The type II error corresponds to the case that the true speed of a vehicle is over 120 kilometers per hour but the driver is not fined. For example, if the true speed of a vehicle μ=125, the probability that the driver is not fined can be calculated as
which means, if the true speed of a vehicle is 125, the driver has the probability of 0.36% to avoid the fine when the statistic is performed at level α=0.05, since the recorded average speed is lower than 121.9. If the true speed is closer to 121.9 than 125, then the probability of avoiding the fine will also be higher.
The tradeoffs between type I error and type II error should also be considered. That is, in this case, if the traffic police do not want to falsely fine innocent drivers, the level α can be set to a smaller value, like 0.01. However, if that is the case, more drivers whose true speed is over 120 kilometers per hour, like 125, would be more likely to avoid the fine.
In 1928, Jerzy Neyman (1894–1981) and Egon Pearson (1895–1980), both eminent statisticians, discussed the problems associated with "deciding whether or not a particular sample may be judged as likely to have been randomly drawn from a certain population": [6] and, as Florence Nightingale David remarked, "it is necessary to remember the adjective 'random' [in the term 'random sample'] should apply to the method of drawing the sample and not to the sample itself". [7]
They identified "two sources of error", namely:
In 1930, they elaborated on these two sources of error, remarking that
in testing hypotheses two considerations must be kept in view, we must be able to reduce the chance of rejecting a true hypothesis to as low a value as desired; the test must be so devised that it will reject the hypothesis tested when it is likely to be false.
In 1933, they observed that these "problems are rarely presented in such a form that we can discriminate with certainty between the true and false hypothesis". They also noted that, in deciding whether to fail to reject, or reject a particular hypothesis amongst a "set of alternative hypotheses", H1, H2..., it was easy to make an error,
[and] these errors will be of two kinds:
- we reject H0 [i.e., the hypothesis to be tested] when it is true, [8]
- we fail to reject H0 when some alternative hypothesis HA or H1 is true. (There are various notations for the alternative).
In all of the papers co-written by Neyman and Pearson the expression H0 always signifies "the hypothesis to be tested".
In the same paper they call these two sources of error, errors of type I and errors of type II respectively. [9]
It is standard practice for statisticians to conduct tests in order to determine whether or not a "speculative hypothesis" concerning the observed phenomena of the world (or its inhabitants) can be supported. The results of such testing determine whether a particular set of results agrees reasonably (or does not agree) with the speculated hypothesis.
On the basis that it is always assumed, by statistical convention, that the speculated hypothesis is wrong, and the so-called "null hypothesis" that the observed phenomena simply occur by chance (and that, as a consequence, the speculated agent has no effect) – the test will determine whether this hypothesis is right or wrong. This is why the hypothesis under test is often called the null hypothesis (most likely, coined by Fisher (1935, p. 19)), because it is this hypothesis that is to be either nullified or not nullified by the test. When the null hypothesis is nullified, it is possible to conclude that data support the "alternative hypothesis" (which is the original speculated one).
The consistent application by statisticians of Neyman and Pearson's convention of representing "the hypothesis to be tested" (or "the hypothesis to be nullified") with the expression H0 has led to circumstances where many understand the term "the null hypothesis" as meaning "the nil hypothesis" – a statement that the results in question have arisen through chance. This is not necessarily the case – the key restriction, as per Fisher (1966), is that "the null hypothesis must be exact, that is free from vagueness and ambiguity, because it must supply the basis of the 'problem of distribution', of which the test of significance is the solution." [10] As a consequence of this, in experimental science the null hypothesis is generally a statement that a particular treatment has no effect; in observational science, it is that there is no difference between the value of a particular measured variable, and that of an experimental prediction.[ citation needed ]
If the probability of obtaining a result as extreme as the one obtained, supposing that the null hypothesis were true, is lower than a pre-specified cut-off probability (for example, 5%), then the result is said to be statistically significant and the null hypothesis is rejected.
British statistician Sir Ronald Aylmer Fisher (1890–1962) stressed that the null hypothesis
is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
— Fisher, 1935, p.19
In the practice of medicine, the differences between the applications of screening and testing are considerable.
Screening involves relatively cheap tests that are given to large populations, none of whom manifest any clinical indication of disease (e.g., Pap smears).
Testing involves far more expensive, often invasive, procedures that are given only to those who manifest some clinical indication of disease, and are most often applied to confirm a suspected diagnosis.
For example, most states in the US require newborns to be screened for phenylketonuria and hypothyroidism, among other congenital disorders.
Although they display a high rate of false positives, the screening tests are considered valuable because they greatly increase the likelihood of detecting these disorders at a far earlier stage.
The simple blood tests used to screen possible blood donors for HIV and hepatitis have a significant rate of false positives; however, physicians use much more expensive and far more precise tests to determine whether a person is actually infected with either of these viruses.
Perhaps the most widely discussed false positives in medical screening come from the breast cancer screening procedure mammography. The US rate of false positive mammograms is up to 15%, the highest in world. One consequence of the high false positive rate in the US is that, in any 10-year period, half of the American women screened receive a false positive mammogram. False positive mammograms are costly, with over $100 million spent annually in the U.S. on follow-up testing and treatment. They also cause women unneeded anxiety. As a result of the high false positive rate in the US, as many as 90–95% of women who get a positive mammogram do not have the condition. The lowest rate in the world is in the Netherlands, 1%. The lowest rates are generally in Northern Europe where mammography films are read twice and a high threshold for additional testing is set (the high threshold decreases the power of the test).
The ideal population screening test would be cheap, easy to administer, and produce zero false negatives, if possible. Such tests usually produce more false positives, which can subsequently be sorted out by more sophisticated (and expensive) testing.
False negatives and false positives are significant issues in medical testing.
False positives can also produce serious and counter-intuitive problems when the condition being searched for is rare, as in screening. If a test has a false positive rate of one in ten thousand, but only one in a million samples (or people) is a true positive, most of the positives detected by that test will be false. The probability that an observed positive result is a false positive may be calculated using Bayes' theorem.
False negatives produce serious and counter-intuitive problems, especially when the condition being searched for is common. If a test with a false negative rate of only 10% is used to test a population with a true occurrence rate of 70%, many of the negatives detected by the test will be false.
This sometimes leads to inappropriate or inadequate treatment of both the patient and their disease. A common example is relying on cardiac stress tests to detect coronary atherosclerosis, even though cardiac stress tests are known to only detect limitations of coronary artery blood flow due to advanced stenosis.
Biometric matching, such as for fingerprint recognition, facial recognition or iris recognition, is susceptible to type I and type II errors.
The probability of type I errors is called the "false reject rate" (FRR) or false non-match rate (FNMR), while the probability of type II errors is called the "false accept rate" (FAR) or false match rate (FMR).
If the system is designed to rarely match suspects then the probability of type II errors can be called the "false alarm rate". On the other hand, if the system is used for validation (and acceptance is the norm) then the FAR is a measure of system security, while the FRR measures user inconvenience level.
False positives are routinely found every day in airport security screening, which are ultimately visual inspection systems. The installed security alarms are intended to prevent weapons being brought onto aircraft; yet they are often set to such high sensitivity that they alarm many times a day for minor items, such as keys, belt buckles, loose change, mobile phones, and tacks in shoes.
The ratio of false positives (identifying an innocent traveler as a terrorist) to true positives (detecting a would-be terrorist) is, therefore, very high; and because almost every alarm is a false positive, the positive predictive value of these screening tests is very low.
The relative cost of false results determines the likelihood that test creators allow these events to occur. As the cost of a false negative in this scenario is extremely high (not detecting a bomb being brought onto a plane could result in hundreds of deaths) whilst the cost of a false positive is relatively low (a reasonably simple further inspection) the most appropriate test is one with a low statistical specificity but high statistical sensitivity (one that allows a high rate of false positives in return for minimal false negatives).
The notions of false positives and false negatives have a wide currency in the realm of computers and computer applications, including computer security, spam filtering, malware, optical character recognition, and many others.
For example, in the case of spam filtering:
While most anti-spam tactics can block or filter a high percentage of unwanted emails, doing so without creating significant false-positive results is a much more demanding task. A low number of false negatives is an indicator of the efficiency of spam filtering.
Biostatistics is a branch of statistics that applies statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results.
Statistics is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of surveys and experiments.
A statistical hypothesis test is a method of statistical inference used to decide whether the data sufficiently supports a particular hypothesis. A statistical hypothesis test typically involves a calculation of a test statistic. Then a decision is made, either by comparing the test statistic to a critical value or equivalently by evaluating a p-value computed from the test statistic. Roughly 100 specialized statistical tests have been defined.
In statistics, the likelihood-ratio test is a hypothesis test that involves comparing the goodness of fit of two competing statistical models, typically one found by maximization over the entire parameter space and another found after imposing some constraint, based on the ratio of their likelihoods. If the more constrained model is supported by the observed data, the two likelihoods should not differ by more than sampling error. Thus the likelihood-ratio test tests whether this ratio is significantly different from one, or equivalently whether its natural logarithm is significantly different from zero.
In scientific research, the null hypothesis is the claim that the effect being studied does not exist. The null hypothesis can also be described as the hypothesis in which no relationship exists between two sets of data or variables being analyzed. If the null hypothesis is true, any experimentally observed effect is due to chance alone, hence the term "null". In contrast with the null hypothesis, an alternative hypothesis is developed, which claims that a relationship does exist between two variables.
In frequentist statistics, power is a measure of the ability of an experimental design and hypothesis testing setup to detect a particular effect if it is truly present. In typical use, it is a function of the test used, the assumed distribution of the test, and the effect size of interest. High statistical power is related to low variability, large sample sizes, large effects being looked for, and less stringent requirements for statistical significance.
In null-hypothesis significance testing, the p-value is the probability of obtaining test results at least as extreme as the result actually observed, under the assumption that the null hypothesis is correct. A very small p-value means that such an extreme observed outcome would be very unlikely under the null hypothesis. Even though reporting p-values of statistical tests is common practice in academic publications of many quantitative fields, misinterpretation and misuse of p-values is widespread and has been a major topic in mathematics and metascience.
In statistical hypothesis testing, the alternative hypothesis is one of the proposed proposition in the hypothesis test. In general the goal of hypothesis test is to demonstrate that in the given condition, there is sufficient evidence supporting the credibility of alternative hypothesis instead of the exclusive proposition in the test. It is usually consistent with the research hypothesis because it is constructed from literature review, previous studies, etc. However, the research hypothesis is sometimes consistent with the null hypothesis.
In statistics, the term "error" arises in two ways. Firstly, it arises in the context of decision making, where the probability of error may be considered as being the probability of making a wrong decision and which would have a different value for each type of error. Secondly, it arises in the context of statistical modelling where the model's predicted value may be in error regarding the observed outcome and where the term probability of error may refer to the probabilities of various amounts of error occurring.
In statistics, the false discovery rate (FDR) is a method of conceptualizing the rate of type I errors in null hypothesis testing when conducting multiple comparisons. FDR-controlling procedures are designed to control the FDR, which is the expected proportion of "discoveries" that are false. Equivalently, the FDR is the expected ratio of the number of false positive classifications to the total number of positive classifications. The total number of rejections of the null include both the number of false positives (FP) and true positives (TP). Simply put, FDR = FP /. FDR-controlling procedures provide less stringent control of Type I errors compared to family-wise error rate (FWER) controlling procedures, which control the probability of at least one Type I error. Thus, FDR-controlling procedures have greater power, at the cost of increased numbers of Type I errors.
In statistics, family-wise error rate (FWER) is the probability of making one or more false discoveries, or type I errors when performing multiple hypotheses tests.
In medicine and statistics, sensitivity and specificity mathematically describe the accuracy of a test that reports the presence or absence of a medical condition. If individuals who have the condition are considered "positive" and those who do not are considered "negative", then sensitivity is a measure of how well a test can identify true positives and specificity is a measure of how well a test can identify true negatives:
Omnibus tests are a kind of statistical test. They test whether the explained variance in a set of data is significantly greater than the unexplained variance, overall. One example is the F-test in the analysis of variance. There can be legitimate significant effects within a model even if the omnibus test is not significant. For instance, in a model with two independent variables, if only one variable exerts a significant effect on the dependent variable and the other does not, then the omnibus test may be non-significant. This fact does not affect the conclusions that may be drawn from the one significant variable. In order to test effects within an omnibus test, researchers often use contrasts.
In statistics, the multiple comparisons, multiplicity or multiple testing problem occurs when one considers a set of statistical inferences simultaneously or estimates a subset of parameters selected based on the observed values.
In statistical hypothesis testing, there are various notions of so-called type III errors, and sometimes type IV errors or higher, by analogy with the type I and type II errors of Jerzy Neyman and Egon Pearson. Fundamentally, type III errors occur when researchers provide the right answer to the wrong question, i.e. when the correct hypothesis is rejected but for the wrong reason.
In statistics, when performing multiple comparisons, a false positive ratio is the probability of falsely rejecting the null hypothesis for a particular test. The false positive rate is calculated as the ratio between the number of negative events wrongly categorized as positive and the total number of actual negative events.
In statistics, a false coverage rate (FCR) is the average rate of false coverage, i.e. not covering the true parameters, among the selected intervals.
A false positive is an error in binary classification in which a test result incorrectly indicates the presence of a condition, while a false negative is the opposite error, where the test result incorrectly indicates the absence of a condition when it is actually present. These are the two kinds of errors in a binary test, in contrast to the two kinds of correct result. They are also known in medicine as a false positivediagnosis, and in statistical classification as a false positiveerror.
In statistical hypothesis testing, specifically multiple hypothesis testing, the q-value in the Storey procedure provides a means to control the positive false discovery rate (pFDR). Just as the p-value gives the expected false positive rate obtained by rejecting the null hypothesis for any result with an equal or smaller p-value, the q-value gives the expected pFDR obtained by rejecting the null hypothesis for any result with an equal or smaller q-value.
In statistical hypothesis testing, the error exponent of a hypothesis testing procedure is the rate at which the probabilities of Type I and Type II decay exponentially with the size of the sample used in the test. For example, if the probability of error of a test decays as , where is the sample size, the error exponent is .
{{cite book}}
: CS1 maint: others (link)