Names | |
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IUPAC name 5,7-dihydroxy-6-methoxy-2-(4-phenoxyphenyl)chromen-4-one | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
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Properties | |
C22H16O6 | |
Molar mass | 376.364 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
5,7-Dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one (DMPC) is a derivative of Oroxylin A.It has memory improving effects and can reduce ADHD-like behavior.
As a derivative of Oroxylin A, it has similar activity; in rats, DMPC has been shown to block the reuptake of dopamine similarly to methylphenidate, however it does not act at the norepinephrine transporter. This has resulted in attenuated ADHD-like behavior, but unlike methylphenidate and other ADHD medication, it did not display addictive properties. Which could make it useful as a non-addictive ADHD drugs, as most currently used ADHD stimulants have addictive properties. [3]
DMPC also possesses memory improving properties, it is able to attenuate memory impairment induced by scopolamine and MK-801. It also had memory-enhancing effects if administered alone. [4]
DMPC is able to block the chloride influx induced by muscimol at GABAA receptors, suggesting that it is a GABAA antagonist or negative modulator. [4]
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron. This results in increased extracellular concentrations of dopamine and increase in dopaminergic neurotransmission.
My 19 Year Old Sister-in-Law is a 2004 South Korean television series starring Jeong Da-bin, Yoon Kye-sang, Kim Jaewon and Kim Min-hee. It aired on SBS from July 28 to September 23, 2004, on Wednesdays and Thursdays at 21:55 for 16 episodes.
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Taejo Wang Geon is a 2000 Korean historical period drama. Directed by Kim Jong-sun and starring Choi Soo-jong in the title role of King Taejo. The drama aired from April 1, 2000, to February 24, 2002, in 200 episodes. The scene dealing with the end of Gungye gained a lot of popularity, recording the highest viewership rating of 60.4% in the metropolitan area.
Thyroid hormone-inducible hepatic protein is a protein that in humans is encoded by the THRSP gene.
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Nonstop (Korean: 논스톱) is a South Korean sitcom that broadcast its first season in 2000 on MBC. It continued with 5 more seasons. The series was popular for its cast of teen idols, many who debuted through the show gaining vast popularity.
Oroxylin A is an O-methylated flavone, a chemical compound that can be found in the medicinal plants Scutellaria baicalensis and Scutellaria lateriflora, and the Oroxylum indicum tree. It has demonstrated activity as a dopamine reuptake inhibitor, and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor. Oroxylin A has been found to improve memory consolidation in mice by elevating brain-derived neurotrophic factor (BDNF) levels in the hippocampus.
South Korea participated in the 2006 Asian Games in Doha, Qatar on 1–15 December 2006. South Korea ranked 2nd with 58 gold medals in this edition of the Asiad.
Jang Bo-ri Is Here! is a 2014 South Korean weekend television drama series broadcast by MBC starring Oh Yeon-seo, Kim Ji-hoon, Lee Yu-ri and Oh Chang-seok. It premiered on April 5, 2014, airing every Saturday and Sunday at 20:40 for 52 episodes. It won Drama of the Year at the 2014 MBC Drama Awards.
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Unknown Woman is a 2017 South Korean television series starring Oh Ji-eun, Bae Jong-ok, Park Yoon-jae, Seo Ji-seok, and Choi Yoon-so. The series aired on KBS2 on Monday to Friday from 7:50 p.m. to 8:30 p.m. (KST).
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You Are a Gift is a 2016 South Korean evening daily drama series starring Heo Yi-jae, Cha Do-jin, Choi Myung-gil, Jin Ye-sol, Kim Cheong, Song Jae-hee, and Shim Ji-ho. It aired on SBS from June 13 to November 24, 2016, airing every Monday to Friday evening at 19:20 for 111 episodes.
The Gentlemen of Wolgyesu Tailor Shop is a 2016 South Korean television series starring Lee Dong-gun, Jo Yoon-hee, Shin Goo, Cha In-pyo, Choi Won-young, Lee Se-young, and Hyun Woo. The series aired on KBS2 every Saturday and Sunday from 7:55 p.m. to 9:15 p.m. (KST). The series served as Kim Young-ae's final work, as she died almost 2 months after the final episode.
Watcher is a 2019 South Korean television series starring Han Suk-kyu, Seo Kang-joon, and Kim Hyun-joo. It aired on OCN every Saturday and Sunday at 22:20 (KST) from July 6 to August 25, 2019.
Find Me in Your Memory is a 2020 South Korean television series starring Kim Dong-wook and Moon Ga-young. It aired on MBC TV from March 18 to May 13, 2020.
BMAPN (βk-methamnetamine) is a substituted cathinone derivative with stimulant effects. It inhibits dopamine reuptake and has rewarding and reinforcing properties in animal studies. It is banned under drug analogue legislation in a number of jurisdictions. The drug was at one point marketed under the name NRG-3, although only a minority of samples of substances sold under this name have been found to actually contain BMAPN, with most such samples containing mixtures of other cathinone derivatives.