Iris (drug)

Last updated

IRIS
IRIS (psychedelic).svg
Clinical data
Other namesIRIS; 2-Methoxy-5-ethoxy-4-methylamphetamine; DOM-5ETO; DOM-5EtO
Routes of
administration
Oral [1]
ATC code
  • None
Pharmacokinetic data
Duration of action Unknown [1]
Identifiers
  • 1-(5-ethoxy-2-methoxy-4-methylphenyl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C13H21NO2
Molar mass 223.316 g·mol−1
3D model (JSmol)
  • COc1cc(C)c(cc1CC(C)N)OCC
  • InChI=1S/C13H21NO2/c1-5-16-12-8-11(7-10(3)14)13(15-4)6-9(12)2/h6,8,10H,5,7,14H2,1-4H3 Yes check.svgY
  • Key:IPJRCKIREPMKNE-UHFFFAOYSA-N Yes check.svgY
   (verify)

Iris, also known as 2-methoxy-5-ethoxy-4-methylamphetamine or as DOM-5ETO, is a drug and a substituted amphetamine. [1] [2] [3] It is also the 5-ethoxy analogue of DOM. [1] [2] [3] The drug was first synthesized by Alexander Shulgin. [1] In his book PiHKAL (Phenethylamines I Have Known and Loved), the minimum dose is listed as 9 mg orally and the duration as unknown. [1] [2] Iris produces few to no effects. [1] [2] Very little data exists about the pharmacological properties, metabolism, and toxicity of IRIS. [1] The drug is one of Shulgin's "ten classic ladies", a series of methylated DOM derivatives. [1] [3] It is not an explicitly controlled substance in the United States, but may be considered scheduled as an isomer of DOET. [4] [5] Iris is a controlled substance in Canada due to phenethylamine blanket-ban language. [6]

Contents

See also

References

  1. 1 2 3 4 5 6 7 8 9 Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN   0-9630096-0-5. OCLC   25627628. IRIS entry
  2. 1 2 3 4 Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN   978-0-12-433951-4. Archived from the original on 13 July 2025.
  3. 1 2 3 Ger A, Ger D. "Triple Goddess of the Night". British Neuroscience Association Bulletin. 63: 28–30.
  4. Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  5. Drug Enforcement Administration (3 December 2007). "Definition of "Positional Isomer" as It Pertains to the Control of Schedule I Controlled Substances". Federal Register.
  6. "Controlled Drugs and Substances Act". Department of Justice Canada. 5 December 2025. Retrieved 20 January 2026.