5-TFM-DMT

Last updated
5-(Trifluoromethyl)-DMT
5-TFM-DMT structure.png
Clinical data
Other names5-TFM-DMT
Identifiers
  • N,N-dimethyl-5-(trifluoromethyl)-1H-Indole-3-ethanamine
CAS Number
PubChem CID
Chemical and physical data
Formula C13H15F3N2
Molar mass 256.272 g·mol−1
3D model (JSmol)
  • CN(C)CCC1=CNC2=CC=C(C(F)(F)F)C=C21
  • InChI=InChI=1S/C13H15F3N2/c1-18(2)6-5-9-8-17-12-4-3-10(7-11(9)12)13(14,15)16/h3-4,7-8,17H,5-6H2,1-2H3
  • Key:VOLQGCCSWTZFGQ-UHFFFAOYSA-N

5-TFM-DMT (5-(trifluoromethyl)-DMT, 5-CF3-DMT, 5-(trifluoromethyl)-N,N-dimethyltryptamine) is a putative psychedelic tryptamine derivative related to drugs such as 5-MeO-DMT, 5-Fluoro-DMT, and 5-TFMO-DMT. It acts as a partial agonist at the 5-HT2A receptor, with an EC50 of 185.7 nM and an efficacy of 28.7% (vs 5-HT), and a full agonist at 5-HT2C with an EC50 of 89.7 nM and an efficacy of 88.8%, and no significant activity at 5-HT2B. [1]

See also

References



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