1,1,2-Trichloroethane

1,1,2-Trichloroethane

1,1,2-Trichloroethane
Names
Preferred IUPAC name 1,1,2-Trichloroethane
Other names 1,1,2-TCA vinyl trichloride symmetrical Trichloroethane monochlorethylen chloride (archaic)
Identifiers
CAS Number	79-00-5  Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:36018  Y
ChEMBL	ChEMBL43882  Y
ChemSpider	6326  Y
ECHA InfoCard	100.001.061
KEGG	C19536  Y
PubChem CID	6574
UNII	28E9ERN9WU  Y
CompTox Dashboard (EPA)	DTXSID5021380
InChI InChI=1S/C2H3Cl3/c3-1-2(4)5/h2H,1H2 Y Key: UBOXGVDOUJQMTN-UHFFFAOYSA-N Y InChI=1/C2H3Cl3/c3-1-2(4)5/h2H,1H2 Key: UBOXGVDOUJQMTN-UHFFFAOYAA
SMILES ClCC(Cl)Cl C(C(Cl)Cl)Cl
Properties
Chemical formula	C2H3Cl3
Molar mass	133.40 g/mol
Appearance	colorless liquid [1]
Odor	sweet, chloroform-like [1] (in high concentrations)
Density	1.435 g/cm3
Melting point	−37 °C (−35 °F; 236 K)
Boiling point	110 to 115 °C (230 to 239 °F; 383 to 388 K)
Solubility in water	0.4% (20°C) [1]
Vapor pressure	19 mmHg (20°C) [1]
Hazards
NFPA 704 (fire diamond)	3 1
Explosive limits	6–15.5% [1]
Lethal dose or concentration (LD, LC):
LD50 (median dose)	1200 mg/kg (rat, orally) [2]
LCLo (lowest published)	13,100 mg/m3 (cat, 4.5 hr) 2000 ppm (rat, 4 hr) [3]
NIOSH (US health exposure limits):
PEL (Permissible)	TWA 10 ppm (45 mg/m3) [skin] [1]
REL (Recommended)	Ca TWA 10 ppm (45 mg/m3) [skin] [1]
IDLH (Immediate danger)	Ca [100 ppm] [1]
Related compounds
Related compounds	1,1,1-Trichloroethane; Trichloroethylene
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y  verify  (what is  YN ?) Infobox references

1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula C₂H₃Cl₃ and the structural formula CH₂Cl−CHCl₂. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene. ^[4]

Toxicity

1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness. ^[5]

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-trichloroethane at 10 ppm over an eight-hour time-weighted average. ^[6]

References

1. NIOSH Pocket Guide to Chemical Hazards. "#0628". National Institute for Occupational Safety and Health (NIOSH).
2. 1,1,2-Trichloroethane toxicity
3. "1,1,2-Trichloroethane". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
4. Toxicological profile for 1,1,2-trichloroethane (PDF) (Report). Agency for Toxic Substances and Disease Registry (ATSDR). March 2021. Archived (PDF) from the original on 2022-03-05. Retrieved 2023-08-23.
5. "Safety (MSDS) data for 1,1,2-trichloroethane" (PDF).
6. CDC - NIOSH Pocket Guide to Chemical Hazards