N-Hydroxymethamphetamine

Last updated

N-Hydroxymethamphetamine
N-Hydroxymethamphetamine.svg
Clinical data
Other namesN-HO-MA; N-hydroxy-NMA; N-Hydroxy-N-methylamphetamine
ATC code
  • None
Identifiers
  • N-methyl-N-(1-phenylpropan-2-yl)hydroxylamine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
Formula C10H15NO
Molar mass 165.236 g·mol−1
3D model (JSmol)
  • CC(CC1=CC=CC=C1)N(C)O
  • InChI=1S/C10H15NO/c1-9(11(2)12)8-10-6-4-3-5-7-10/h3-7,9,12H,8H2,1-2H3
  • Key:PCDVFYKROPOLBF-UHFFFAOYSA-N

N-Hydroxymethamphetamine (N-HO-MA or N-hydroxy-NMA) is a known metabolite of the stimulant drug methamphetamine. [1] [2] [3]

Contents

See also

References

  1. ↑ Abbruscato TJ, Trippier PC (October 2018). "DARK Classics in Chemical Neuroscience: Methamphetamine". ACS Chemical Neuroscience. 9 (10): 2373–2378. doi:10.1021/acschemneuro.8b00123. PMID   29602278. Figure 1. Metabolic pathway of methamphetamine in humans.
  2. ↑ Coutts RT, Kovach SH (June 1977). "Metabolism in vitro of N-methylamphetamine with rat liver homogenates". Biochemical Pharmacology. 26 (11): 1043–1049. doi:10.1016/0006-2952(77)90242-8. PMID   18150.
  3. ↑ Baba T, Yamada H, Oguri K, Yoshimura H (May 1988). "Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine". Xenobiotica; The Fate of Foreign Compounds in Biological Systems. 18 (5): 475–484. doi:10.3109/00498258809041684. PMID   3135673.
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