5-HO-MET

Last updated

5-HO-MET
5-OH-MET.svg
Clinical data
Other names5-OH-MET; 5-Hydroxy-MET; 5-Hydroxy-N-methyl-N-ethyltryptamine
Drug class Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • 3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-5-ol
PubChem CID
Chemical and physical data
Formula C13H18N2O
Molar mass 218.300 g·mol−1
3D model (JSmol)
  • CCN(C)CCC1=CNC2=C1C=C(C=C2)O
  • InChI=1S/C13H18N2O/c1-3-15(2)7-6-10-9-14-13-5-4-11(16)8-12(10)13/h4-5,8-9,14,16H,3,6-7H2,1-2H3
  • Key:BQUBMTNAIITQAI-UHFFFAOYSA-N

5-HO-MET, also known as 5-hydroxy-N-methyl-N-ethyltryptamine, is a psychedelic drug of the tryptamine and 5-hydroxytryptamine families related to bufotenin (5-HO-DMT). [1] It is the derivative of bufotenin in which one of the two methyl groups at the amine has been extended to an ethyl group. [1] The drug is also an analogue of methylethyltryptamine (MET), 4-HO-MET (metocin), and 5-MeO-MET. [1] 5-HO-MET was reported as a novel designer drug in Canada in 2025. [1] Its predicted log P is 1.6, [2] relative to 1.2 in the case of bufotenin. [3]

See also

References

  1. 1 2 3 4 Rymill S, Candler L, Ramachandran P, Bacev-Giles C, Ngendabanka RJ, Racine S, et al. (2025). "New psychoactive substances (NPS) identified in Canada: Results of the online NPS survey (2020–2023)". Emerging Trends in Drugs, Addictions, and Health. 5 100178. doi:10.1016/j.etdah.2025.100178 . Retrieved 5 January 2026.
  2. ↑ "3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-5-ol". PubChem. Retrieved 5 January 2026.
  3. ↑ "Bufotenine". PubChem. Retrieved 5 January 2026.
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