Methylallyltryptamine

Last updated

MALT
Methylallyltryptamine.svg
MALT 3D.png
Clinical data
Other namesMALT; N,N-Methylallyltyptamine
Routes of
administration 		Oral, smoking, vaping [1]
Drug class Serotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Onset of action Unknown [1] [2]
Duration of action Unknown [1] [2]
Identifiers
  • N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C14H18N2
Molar mass 214.312 g·mol−1
3D model (JSmol)
  • CN(CCC1=CNC2=CC=CC=C21)CC=C
  • InChI=1S/C14H18N2/c1-3-9-16(2)10-8-12-11-15-14-7-5-4-6-13(12)14/h3-7,11,15H,1,8-10H2,2H3
  • Key:GXCLVBGFBYZDAG-UHFFFAOYSA-N

Methylallyltryptamine (MALT), also known as N-methyl-N-allyltryptamine, is a lesser-known psychedelic drug from the tryptamine family. [1] It is a novel compound with very little history of human use. [1] It is closely related to methylpropyltryptamine (MPT). [1] The drug has been sold online as a designer drug. [1] Very little information on the pharmacology or toxicity of MALT is available.[ citation needed ]

Contents

Use and effects

MALT was not included in Alexander Shulgin's 1997 book TiHKAL (Tryptamines I Have Known and Loved). [2] However, years after the book's publication, he described MALT as having important unexplored potential as a psychedelic drug. [3] Subsequently, MALT was encountered as a novel designer drug. [1] It has been reported to have been used at doses of 25 to 50 mg via routes including oral, smoking, or vaping. [1] The drug's effects have been described as comparable to those of methylpropyltryptamine (MPT) but less pronounced. [1]

Interactions

Pharmacology

Pharmacodynamics

MALT is a serotonin receptor modulator and has been found to interact with the serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors. [4]

Chemistry

Analogues

Analogues of MALT include 4-HO-MALT, 4-AcO-MALT, 5-MeO-MALT, diallyltryptamine (DALT), methylpropyltryptamine (MPT), and methylisopropyltryptamine (MiPT), among others.

History

MALT was first described in the scientific literature by Niels Jensen of the University of Göttingen by 2004. [4] The drug was subsequently first encountered as a novel designer drug by 2018. [1]

Society and culture

A ziplock bag containing 100mg of MALT crystals, labeled "Not for human consumption". N,N-methylallyltryptamine.jpg
A ziplock bag containing 100mg of MALT crystals, labeled "Not for human consumption".

MALT is not explicitly scheduled in any countries; however, it could be considered a psychoactive substance under the United Kingdom Psychoactive Substances Act, which requires the prosecutor to prove that the substance is psychoactive in order for a person to be charged with an offense. [5] It could also be considered a structural analogue of a scheduled substance under the United States Federal Analogue Act due to its similarity to scheduled tryptamines.

See also

References

  1. 1 2 3 4 5 6 7 8 9 10 11 https://isomerdesign.com/bitnest/aipsin/13.%20Issue%2011,%20Nov%202020.pdf
  2. 1 2 3 Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN   0-9630096-9-9. OCLC   38503252.
  3. ↑ Morris H (2014). "Alexander Shulgin (1925–2014)". The Fabulist. No. 5. On that day in 2010, Alexander Shulgin was sitting outside under a parasol in his front yard surrounded by admirers, looking very happy, and talking discursively about the unexplored potential in 5-ethoxylated tryptamines and asymmetrical N-allyl-tryptamines such as MAlT, EAlT, PAlT, and iPAlT
  4. 1 2 Jensen N (2004). Tryptamines as Ligands and Modulators of the Serotonin 5‑HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens (PDF) (Thesis). Georg-August-University Göttingen. doi: 10.53846/goediss-2111 .
  5. ↑ "Psychoactive Substances Act Guidance" (PDF). The Crown Prosecution Service. Retrieved 2021-09-23.
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